Factors that influence disease-specific quality of life or health status in patients with COPD: a review and meta-analysis of Pearson correlations.
Factors that influence disease-specific quality of life or health status in patients with COPD: a review and meta-analysis of Pearson correlations.
复制标题
影响慢性阻塞性肺病患者特定疾病生活质量或健康状况的因素：皮尔逊相关性的回顾和荟萃分析。
DOI：
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复制
发表时间：
2011
影响因子：
--
通讯作者：
T. van der Molen
中科院分区：
文献类型：
--
作者：
I. Tsiligianni;J. Kocks;N. Tzanakis;N. Siafakas;T. van der Molen
背景
慢性阻塞性肺疾病 (COPD) 治疗的一个主要目标是确保 COPD 患者的疾病负担有限，并确保患者拥有尽可能最佳的生活质量。
目标管理系统
探讨可能影响慢性阻塞性肺病患者疾病特异性生活质量和健康状况的所有可能因素。
方法
我们对文献进行了系统回顾和荟萃分析，以探讨可能对慢性阻塞性肺病患者的生活质量和/或健康状况产生积极或消极影响的因素。
结果
生活质量和健康状况由某些因素决定，包括性别、疾病严重程度指数、肺功能参数、体重指数、吸烟、症状、共病、抑郁、焦虑和病情加重。研究发现，与广泛使用的肺量测定值相比，呼吸困难、抑郁、焦虑和运动耐量等因素与健康状况的相关性更大。一秒用力呼气量具有弱到适度的皮尔逊加权相关系数，其范围从 -0.110 到 -0.510，具体取决于所使用的调查问卷。
结论
广泛的决定因素表明，为了达到管理目标，除了肺功能外，还应该测量慢性阻塞性肺病患者的健康状况。
BACKGROUND
A major goal in the management of chronic obstructive pulmonary disease (COPD) is to ensure that the burden of the disease for patients with COPD is limited and that patients will have the best possible quality of life.
AIMS
To explore all the possible factors that could influence disease-specific quality of life and health status in patients with COPD.
METHODS
A systematic review of the literature and a meta-analysis were performed to explore the factors that could have a positive or negative effect on quality of life and/or health status in patients with COPD.
RESULTS
Quality of life and health status are determined by certain factors included gender, disease severity indices, lung function parameters, body mass index, smoking, symptoms, co-morbidity, depression, anxiety, and exacerbations. Factors such as dyspnoea, depression, anxiety and exercise tolerance were found to be more correlated with health status than the widely used spirometric values. Forced expiratory volume in one second had a weak to modest Pearson weighted correlation coefficient which ranged from -0.110 to -0.510 depending on the questionnaire used.
CONCLUSIONS
The broad range of determining factors suggests that, in order to reach the management goals, health status should be measured in addition to lung function in patients with COPD.
影响因子：
--
作者：
Moy ML;Reilly JJ;Ries AL;Mosenifar Z;Kaplan RM;Lew R;Garshick E;National Emphysema Treatment Trial Research Group
通讯作者：
National Emphysema Treatment Trial Research Group
影响因子：
9.6
作者：
Eisner, MD;Trupin, L;Blanc, PD
通讯作者：
Blanc, PD
DOI：
10.1016/0021-9681(84)90050-x
发表时间：
1984-01-01
期刊：
JOURNAL OF CHRONIC DISEASES
影响因子：
--
作者：
KAPLAN, RM;ATKINS, CJ;TIMMS, R
通讯作者：
TIMMS, R