Optical fiber LSPR biosensor prepared by gold nanoparticle assembly on polyelectrolyte multilayer.
Optical fiber LSPR biosensor prepared by gold nanoparticle assembly on polyelectrolyte multilayer.
复制标题
聚电解质多层膜上金纳米颗粒组装制备光纤LSPR生物传感器
DOI:
10.3390/s100403585
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发表时间:
2010
期刊:
影响因子:
--
通讯作者:
Xu W
中科院分区:
文献类型:
--
作者:
Shao Y;Xu S;Zheng X;Wang Y;Xu W
This article provides a novel method of constructing an optical fiber localized surface plasmon resonance (LSPR) biosensor. A gold nanoparticle (NP) assembled film as the sensing layer was built on the polyelectrolyte (PE) multilayer modified sidewall of an unclad optical fiber. By using a trilayer PE structure, we obtained a monodisperse gold NP assembled film. The preparation procedure for this LSPR sensor is simple and time saving. The optical fiber LSPR sensor has higher sensitivity and outstanding reproducibility. The higher anti-interference ability for response to an antibody makes it a promising method in application as a portable immuno-sensor.
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