The cell cycle dependence of the secretory pathway in developing Xenopus laevis.
The cell cycle dependence of the secretory pathway in developing Xenopus laevis.
复制标题
发育中非洲爪蟾分泌途径的细胞周期依赖性。
DOI：
10.1016/0012-1606(91)90461-b
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发表时间：
1991
影响因子：
2.7
通讯作者：
Newport,JW
中科院分区：
文献类型：
--
作者：
Kanki,JP;Newport,JW
The cell cycle during the cleavage period of the amphibianXenopus laevisis about 30 min long and oscillates between equal periods of mitosis and interphase. At the midblastula transition (MBT) the length of interphase begins to elongate and brings about corresponding changes in the activities of cell cycle-dependent processes. In this study protein secretion and Golgi processing during embryonicXenopusdevelopment were examined. The elongation of interphase, either during normal development or experimentally induced, resulted in an increase in the secretion of both endogenous and exogenous proteins. Secretion was found to increase linearly with the increase in interphase length, indicating that the rate of secretion was constant and was regulated by the length of interphase. M-phase arrest in embryos and oocytes produced an inhibition of protein secretion that was reversible if the cell cycle was returned to interphase. This M-phase block of the secretory pathway was found to take place between the trans Golgi compartment and the plasma membrane. The developmental increase in the function of this pathway after the MBT may affect the expression of surface and secreted proteins important for the cell-cell interactions necessary for subsequent development through gastrulation.
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显微注射 p34cdc2 的保守肽序列会在卵母细胞中诱导 Ca2 瞬变。
影响因子：
56.9
作者：
A. Picard;J. Cavadore;P. Lory;J. Bernengo;C. Ojeda;M. Dorée
通讯作者：
M. Dorée
影响因子：
2.7
作者：
LEAF, DS;ROBERTS, SJ;MOORE, HP
通讯作者：
MOORE, HP
早期胚胎细胞类型差异的起源。
DOI：
10.1016/0922-3371(88)90092-5
发表时间：
1988
期刊：
Cell differentiation and development : the official journal of the International Society of Developmental Biologists
影响因子：
--
作者：
J. Gurdon
通讯作者：
J. Gurdon
影响因子：
3.3
作者：
Guo Y;Chen F;Cui W
通讯作者：
Cui W
DOI：
10.1083/jcb.109.4.1439
发表时间：
1989-10
期刊：
The Journal of cell biology
影响因子：
--
作者：
Ceriotti A;Colman A
通讯作者：
Colman A