Coercing bisphosphonates to kill cancer cells with nanoscale coordination polymers.

Coercing bisphosphonates to kill cancer cells with nanoscale coordination polymers.
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DOI:
10.1039/c2cc17635a
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发表时间:
2012-03-11
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Lin W
Lin W
中科院分区:
其他
文献类型:
--
作者:
Liu D;Kramer SA;Huxford-Phillips RC;Wang S;Della Rocca J;Lin W

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Nanoscale coordination polymers containing exceptionally high loadings of bisphosphonates were coated with single lipid bilayers to control the drug release kinetics and functionalized with a targeting ligand to endow cell-targeting capability, leading to much enhanced cytotoxicity against human lung and pancreatic cancer cells.
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