The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol.
The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol.
复制标题
DOI：
10.1093/g3journal/jkab423
复制
发表时间：
2022-02-04
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
斑马贻贝是世界上最具破坏性的入侵物种之一。它们原产于欧亚大陆，继续在欧洲和近几十年来在北美迅速传播，造成数十亿美元的经济损失，并极大地改变了受感染的湖泊和河流的生态系统。在这里，我们报告了斑马贻贝基因组的测序，这将成为入侵物种研究和生物防治工作的重要工具。斑马贻贝（Dreissena polymorpha）继续从欧亚大陆的原生地传播到欧洲和北美，造成了数十亿美元的损失，并极大地改变了被入侵的水生生态系统。尽管存在这些影响，Dreissena 或相关双壳类的基因组资源却很少。尽管地精基因组高度重复，但我们结合使用长读长测序和基于 Hi-C 的支架来生成高质量的染色体规模基因组组装。通过比较分析和转录组学实验，我们深入了解了可能控制斑马贻贝成功入侵的过程，包括壳的形成、足丝的合成和耐热性。我们发现了多个完整的类似蒸笼的元件，这是一种与海洋蛤中的传染性癌症有关的逆转录转座子。我们还发现地精有一个不寻常的 67 kb 线粒体基因组，其中包含大量串联重复，使其成为真后生动物中观察到的最大的线粒体基因组。这些发现共同为入侵物种研究和控制工作创造了丰富的资源。
Zebra mussels are one of the world’s most damaging invasive species. Native to Eurasia, they have continued to spread rapidly though Europe and in recent decades through North America, causing billions of dollars in economic damage and dramatically altering the ecosystems of infested lakes and rivers. Here we report the sequencing of the zebra mussel genome which will be an important tool for invasive species research and biocontrol efforts. The zebra mussel, Dreissena polymorpha, continues to spread from its native range in Eurasia to Europe and North America, causing billions of dollars in damage and dramatically altering invaded aquatic ecosystems. Despite these impacts, there are few genomic resources for Dreissena or related bivalves. Although the D. polymorpha genome is highly repetitive, we have used a combination of long-read sequencing and Hi-C-based scaffolding to generate a high-quality chromosome-scale genome assembly. Through comparative analysis and transcriptomics experiments, we have gained insights into processes that likely control the invasive success of zebra mussels, including shell formation, synthesis of byssal threads, and thermal tolerance. We identified multiple intact steamer-like elements, a retrotransposon that has been linked to transmissible cancer in marine clams. We also found that D. polymorpha have an unusual 67 kb mitochondrial genome containing numerous tandem repeats, making it the largest observed in Eumetazoa. Together these findings create a rich resource for invasive species research and control efforts.
登录
查看更多内容
影响因子：
6.5
作者：
Anisimova M;Gil M;Dufayard JF;Dessimoz C;Gascuel O
通讯作者：
Gascuel O
对血蛤 Tegillarca granosa 中软体动物红血性起源和进化的基因组见解。
影响因子：
10.7
作者：
Bao Y;Zeng Q;Wang J;Zhang Z;Zhang Y;Wang S;Wong NK;Yuan W;Huang Y;Zhang W;Liu J;Lv L;Xue Q;Zha S;Peng Z;Yao H;Bao Z;Wang S;Lin Z
通讯作者：
Lin Z
影响因子：
4.9
作者：
Bao W;Kojima KK;Kohany O
通讯作者：
Kohany O
影响因子：
1.9
作者：
Breton, Sophie;Stewart, Donald T.;Hoeh, Walter R.
通讯作者：
Hoeh, Walter R.
DOI：
10.1073/pnas.1409945111
发表时间：
2014-09-30
影响因子：
11.1
作者：
Arriagada, Gloria;Metzger, Michael J.;Goff, Stephen P.
通讯作者：
Goff, Stephen P.