The Effect and Optimal Parameters of Repetitive Transcranial Magnetic Stimulation on Poststroke Dysphagia: A Meta-Analysis of Randomized Controlled Trials.

The Effect and Optimal Parameters of Repetitive Transcranial Magnetic Stimulation on Poststroke Dysphagia: A Meta-Analysis of Randomized Controlled Trials.
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重复经颅磁刺激对卒中后吞咽困难的影响及最佳参数:随机对照试验的Meta分析。

DOI:
10.3389/fnins.2022.845737
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发表时间:
2022
影响因子:
4.3
通讯作者:
Dou, Zu-lin
Dou, Zu-lin
中科院分区:
医学2区
文献类型:
--
作者:
Qiao, Jia;Ye, Qiu-ping;Wu, Zhi-min;Dai, Yong;Dou, Zu-lin

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The objectives of the study were to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) treatment for poststroke dysphagia (PSD) and explore the optimal stimulation parameters. The databases of Medline, Embase, Web of Science, and Cochrane Library were searched from the establishment to June 2021. All randomized controlled trials about rTMS treatment for PSD were enrolled. Dysphagia Grade (DG) and Penetration Aspiration Scale (PAS) were applied as the major dysphagia severity rating scales to evaluate the outcomes. A total of 12 clinical randomized controlled studies were included in our study. The summary effect size indicated that rTMS had a positive effect on PSD (SMD = −0.67, p < 0.001). The subgroup analysis for treatment duration and different stroke stages showed significant differences (treatment duration >5 days: SMD = −0.80, p < 0.001; subacute phase after stroke: SMD = −0.60, p < 0.001). Furthermore, no significant differences were observed among the other stimulation parameter subgroups (including stimulation frequency, location, and a single stimulation time) (p > 0.05). rTMS is beneficial to the recovery of PSD patients, while an intervention of more than 5 days and in the subacute phase after stroke might bring new strategies and rational therapeutics to the treatment of PSD. http://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022299469.
通过重复的经颅磁刺激(RTMS)从抑郁症中恢复:临床前研究的系统综述和荟萃分析。
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