Laparoscopic versus open resection for gastric gastrointestinal stromal tumors: an updated systematic review and meta-analysis.
Laparoscopic versus open resection for gastric gastrointestinal stromal tumors: an updated systematic review and meta-analysis.
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腹腔镜胃肠道胃肠道肿瘤的腹腔镜与开放切除：一项更新的系统审查和荟萃分析。
DOI：
10.1186/1477-7819-12-206
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发表时间：
2014-07-14
影响因子：
3.2
通讯作者：
Mou YP
中科院分区：
文献类型：
--
作者：
Chen QL;Pan Y;Cai JQ;Wu D;Chen K;Mou YP
在过去的几十年中，腹腔镜手术已被引入用于治疗胃肠道间质瘤（GIST）。最近，已经发表了比较腹腔镜手术与开放手术治疗胃GIST的其他研究，并且有必要对该主题进行更新的荟萃分析。在PubMed、Embase、科克伦图书馆和Web of Science中进行了系统检索。从数据库中识别出2014年6月之前发表的腹腔镜和开放手术治疗胃GIST的比较研究。采用Newcastle-Ottawa质量评估量表进行质量评估，并提取原始数据。采用统计软件STATA（12.0版）进行Meta分析。最后，22项研究，包括总共1，166例病例，符合荟萃分析的纳入标准。腹腔镜手术与开腹手术的手术时间相似。与开放手术相比，腹腔镜切除术失血量较少（WMD = -58.91 ml; 95% CI，-84.60至-33.22 ml; P <0.01）;较早排气时间（WMD = -1.31 d; 95%CI，-1.56至-1.06，P <0.01）（WMD = -1.75 d; 95% CI，-2.12至-1.39; P <0.01）;住院时间缩短（WMD = -3.68 d; 95%CI，-4.47 to -2.88; P <0.01）;总体并发症减少（相对危险度= 0.57; 95%CI，0.37 to 0.89; P = 0.01）。对于长期结局，两种手术方法在复发方面没有显著差异。腹腔镜手术治疗胃GISTs是可以接受的选择性患者与更好的短期结果相比，开放手术。患者的长期生存情况主要取决于肿瘤本身的性质，腹腔镜手术与肿瘤预后不良无关。
In past decades, laparoscopic surgery has been introduced for the treatment of gastrointestinal stromal tumors (GISTs). Recently, additional studies comparing laparoscopic versus open surgery for gastric GISTs have been published, and an updated meta-analysis of this subject is necessary. A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science. Comparative studies of laparoscopic and open surgery for gastric GISTs published before June 2014 were identified from databases. The Newcastle-Ottawa Quality Assessment Scale was used to perform quality assessment and original data were extracted. The statistical software STATA (version 12.0) was used for the meta-analysis. Finally, 22 studies, including a total of 1,166 cases, meet the inclusion criteria for meta-analysis. The operation time was similar between laparoscopic and open surgery. Compared to open surgery, laparoscopic resection was associated withless blood loss (WMD = -58.91 ml; 95% CI, -84.60 to -33.22 ml; P <0.01); earlier time to flatus (WMD = -1.31 d; 95% CI, -1.56 to -1.06, P <0.01) and oral diet (WMD = -1.75 d; 95% CI, -2.12 to -1.39; P <0.01); shorter hospital stay (WMD = -3.68 d; 95% CI, -4.47 to -2.88; P <0.01); and decreased overall complications (relative risk = 0.57; 95% CI, 0.37 to 0.89; P = 0.01). For long-term outcomes, there were no significant differences between two surgical procedures on recurrence. Laparoscopic surgery for gastric GISTs is acceptable for selective patients with better short-term outcomes compared with open surgery. The long-term survival situation of patients mainly depends on the nature of tumor itself, and laparoscopic surgery was not associated with worse oncological outcomes.
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影响因子：
4
作者：
Hozo SP;Djulbegovic B;Hozo I
通讯作者：
Hozo I
DOI：
10.1097/00129689-200604000-00005
发表时间：
2006-04-01
影响因子：
1
作者：
Ishikawa, K;Inomata, M;Kitano, S
通讯作者：
Kitano, S
影响因子：
3.2
作者：
Kim KH;Kim MC;Jung GJ;Kim SJ;Jang JS;Kwon HC
通讯作者：
Kwon HC
DOI：
10.1007/s00464-012-2622-8
发表时间：
2013-05-01
影响因子：
3.1
作者：
De Vogelaere, Kristel;Hoorens, Anne;Delvaux, Georges
通讯作者：
Delvaux, Georges
DOI：
10.1089/lap.2012.0115
发表时间：
2012-10-01
影响因子：
1.3
作者：
Chen, Yu-Hsien;Liu, Keng-Hao;Yeh, Ta-Sen
通讯作者：
Yeh, Ta-Sen