Unprecedented Fluorophore Photostability Enabled by Low-Loss Organic Hyperbolic Materials.
Unprecedented Fluorophore Photostability Enabled by Low-Loss Organic Hyperbolic Materials.
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低损耗有机双曲材料实现了前所未有的荧光团光稳定性。
DOI：
10.1002/adma.202006496
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Liu Z
中科院分区：
文献类型：
--
作者：
Lee YU;Li S;Bopp SE;Zhao J;Nie Z;Posner C;Yang S;Zhang X;Zhang J;Liu Z
荧光分子中的光子动力学在荧光成像、光学传感、有机光致发光和显示中起着关键作用。光漂白是荧光团的不可逆光降解过程，代表了相关光学应用中的基本限制。化学试剂已被用来抑制光漂白率，但具有非常高的特异性，每种类型的荧光团。在这里，使用有机双曲材料（欧姆），我们展示了一个光学平台，以实现前所未有的荧光团光稳定性，没有任何化学特异性。同时观察到光漂白寿命延长500倍以上，总发射光子数增加230倍。这些特殊的改进仅仅来自于OHM薄膜的低损耗双曲线色散和在可见光谱范围内的大的合成珀塞尔效应。所展示的OHM平台可能为纳米光子学和有机等离子体超分辨率成像和纳米级光物质相互作用的工程开辟新的范例。荧光团在欧姆上比在玻璃上更对光稳定。在玻璃基板上，荧光团几乎立即被光漂白;然而，在欧姆基板上观察到高度光稳定的荧光团。荧光团的光漂白寿命延长了四个数量级，光子计数增加了230倍。
The dynamics of photons in fluorescent molecules plays a key role in fluorescence imaging, optical sensing, organic photovoltaics, and displays. Photobleaching is an irreversible photodegradation process of fluorophores, representing a fundamental limitation in relevant optical applications. Chemical reagents have been used to suppress the photobleaching rate but with exceptionally high specificity for each type of fluorophore. Here, using organic hyperbolic materials (OHMs), we demonstrate an optical platform to achieve unprecedented fluorophore photostability without any chemical specificity. A more than 500-fold lengthening of the photobleaching lifetime and a 230-fold increase in the total emitted photon counts were observed simultaneously. These exceptional improvements solely come from the low loss hyperbolic dispersion of OHM films and the large resultant Purcell effect in the visible spectral range. The demonstrated OHM platform may open up a new paradigm in nanophotonics and organic plasmonics for super-resolution imaging and the engineering of light-matter interactions at nanoscale. Fluorophores are much more photostable on OHMs than on glass. On the glass substrate, fluorophores are photobleached almost immediately; highly photostable fluorophores, however, are observed on the OHM substrate. Fluorophore photobleaching lifetimes were lengthened up to four orders of magnitude with a 230-fold increase in photon counts.
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影响因子：
4.6
作者：
Lin HI;Shen KC;Lin SY;Haider G;Li YH;Chang SW;Chen YF
通讯作者：
Chen YF
影响因子：
35
作者：
Chizhik, Alexey I.;Rother, Jan;Enderlein, Joerg
通讯作者：
Enderlein, Joerg
影响因子：
4
作者：
Jacob, Zubin;Smolyaninov, Igor I.;Narimanov, Evgenii E.
通讯作者：
Narimanov, Evgenii E.
DOI：
10.1073/pnas.0907866106
发表时间：
2009-12-29
影响因子：
11.1
作者：
Dertinger, T.;Colyer, R.;Enderlein, J.
通讯作者：
Enderlein, J.
影响因子：
9
作者：
Lee, Yeon Ui;Garoni, Eleonora;D'Aleo, Anthony
通讯作者：
D'Aleo, Anthony