TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels.
TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels.
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DOI：
10.1093/nar/gkl925
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
Paulsen IT
中科院分区：
文献类型：
--
作者：
Ren Q;Chen K;Paulsen IT
TransportDB（）是一个完整基因组序列的生物细胞质膜转运蛋白和外膜通道信息的综合数据库资源。基于一系列的实验和生物信息学证据，对每种生物的一整套膜运输系统和外膜通道进行了注释，并根据其运输方式、生物能量学、分子系统发育和底物特异性将其分类为不同的类型和科。设计了用户友好的网页界面，方便访问、查询和下载数据。TransportDB网站的特点包括基于文本和BLAST的搜索工具，针对已知的转运蛋白和外膜通道蛋白；不同生物转运体和外膜通道含量的比较已知的转运蛋白的三维结构和转运蛋白家族的系统发育树。在单个蛋白质页面上，用户可以找到详细的功能注释、支持生物信息学证据、蛋白质/DNA序列、出版物和交叉引用的外部在线资源链接。TransportDB现在已经存在了10多年，并继续定期更新来自新测序基因组的新证据和数据，并定期添加新功能。
TransportDB () is a comprehensive database resource of information on cytoplasmic membrane transporters and outer membrane channels in organisms whose complete genome sequences are available. The complete set of membrane transport systems and outer membrane channels of each organism are annotated based on a series of experimental and bioinformatic evidence and classified into different types and families according to their mode of transport, bioenergetics, molecular phylogeny and substrate specificities. User-friendly web interfaces are designed for easy access, query and download of the data. Features of the TransportDB website include text-based and BLAST search tools against known transporter and outer membrane channel proteins; comparison of transporter and outer membrane channel contents from different organisms; known 3D structures of transporters, and phylogenetic trees of transporter families. On individual protein pages, users can find detailed functional annotation, supporting bioinformatic evidence, protein/DNA sequences, publications and cross-referenced external online resource links. TransportDB has now been in existence for over 10 years and continues to be regularly updated with new evidence and data from newly sequenced genomes, as well as having new features added periodically.
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影响因子：
5.8
作者：
Zmasek, CM;Eddy, SR
通讯作者：
Eddy, SR
Pfam：氏族、网络工具和服务。
影响因子：
14.9
作者：
Finn, Robert D.;Mistry, Jaina;Schuster-Bockler, Benjamin;Griffiths-Jones, Sam;Hollich, Volker;Lassmann, Timo;Moxon, Simon;Marshall, Mhairi;Khanna, Ajay;Durbin, Richard;Eddy, Sean R.;Sonnhammer, Erik L. L.;Bateman, Alex
通讯作者：
Bateman, Alex
影响因子：
14.9
作者：
Ren, QH;Kang, KH;Paulsen, IT
通讯作者：
Paulsen, IT
影响因子：
14.9
作者：
Tatusov, RL;Natale, DA;Koonin, EV
通讯作者：
Koonin, EV
影响因子：
7
作者：
Tomii, K;Kanehisa, M
通讯作者：
Kanehisa, M