The Dementias Platform UK (DPUK) Data Portal
The Dementias Platform UK (DPUK) Data Portal
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英国痴呆症平台 (DPUK) 数据门户
DOI:
10.1101/582155
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Bauermeister S
中科院分区:
文献类型:
--
作者:
Bauermeister S
The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure ‘lab’ using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.
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DOI:
10.1186/s13195-017-0288-0
发表时间:
2017-08-29
期刊:
Alzheimer's research & therapy
影响因子:
--
作者:
Dufouil C;Dubois B;Vellas B;Pasquier F;Blanc F;Hugon J;Hanon O;Dartigues JF;Harston S;Gabelle A;Ceccaldi M;Beauchet O;Krolak-Salmon P;David R;Rouaud O;Godefroy O;Belin C;Rouch I;Auguste N;Wallon D;Benetos A;Pariente J;Paccalin M;Moreaud O;Hommet C;Sellal F;Boutoleau-Bretonniére C;Jalenques I;Gentric A;Vandel P;Azouani C;Fillon L;Fischer C;Savarieau H;Operto G;Bertin H;Chupin M;Bouteloup V;Habert MO;Mangin JF;Chêne G;MEMENTO cohort Study Group
通讯作者:
MEMENTO cohort Study Group
影响因子:
4.1
作者:
Deary IJ;Gow AJ;Taylor MD;Corley J;Brett C;Wilson V;Campbell H;Whalley LJ;Visscher PM;Porteous DJ;Starr JM
通讯作者:
Starr JM
DOI:
10.17863/cam.6890
发表时间:
2017
期刊:
--
影响因子:
--
作者:
Bevan Jones R
通讯作者:
Bevan Jones R
DOI:
--
发表时间:
2018
期刊:
Journal of Cachexia, Sarcopenia and Muscle
影响因子:
--
作者:
J. Yoo;Mi;Jae‐Bum Na;Yun‐Hong Chun;Young;Yongwhi Park;Young;Y. Ha;Ki
通讯作者:
Ki
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
Rosann Torres;Brenda Yessenia Olalde Vázquez
通讯作者:
Brenda Yessenia Olalde Vázquez