Treatment of Iron Deficiency in Heart Failure.

Treatment of Iron Deficiency in Heart Failure.
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DOI:
10.1007/s11886-023-01889-4
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发表时间:
2023-07
影响因子:
3.7
通讯作者:
McDonagh, Theresa. A. A.
McDonagh, Theresa. A. A.
中科院分区:
医学3区
文献类型:
--
作者:
Shamsi, Aamir;Cannata, Antonio;Piper, Susan;Bromage, Daniel. I. I.;McDonagh, Theresa. A. A.

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心力衰竭 (HF) 通常与缺铁 (ID) 相关,缺铁定义为铁含量不足以满足生理需求。 ID 与贫血的关系已广为人知,但人们越来越认识到,即使没有贫血,它也是心力衰竭的重要合并症。本综述总结了 HFrEF 和 HFpEF 中 ID 的测量和治疗以及特定 HF 病因的当代证据,并强调了证据基础中的重要差距。 ID 在心力衰竭患者中很常见,并且与发病率和死亡率增加相关。纠正心力衰竭患者的 ID 可以影响功能状态、运动耐量、症状和整体生活质量,无论贫血状况如何。 ID 是心力衰竭的一种可改变的合并症。因此,识别和治疗智力障碍具有新兴的治疗潜力,对于所有护理心力衰竭患者的临床医生来说,了解治疗的基本原理和方法非常重要。
Heart failure (HF) is commonly associated with iron deficiency (ID), defined as insufficient levels of iron to meet physiological demands. ID’s association with anaemia is well understood but it is increasingly recognised as an important comorbidity in HF, even in the absence of anaemia. This review summarises contemporary evidence for the measurement and treatment of ID, in both HFrEF and HFpEF, and specific HF aetiologies, and highlights important gaps in the evidence-base. ID is common among patients with HF and associated with increased morbidity and mortality. Correcting ID in patients with HF can impact upon functional status, exercise tolerance, symptoms, and overall quality of life, irrespective of anaemia status. ID is a modifiable comorbidity in HF. Therefore, recognising and treating ID has emerging therapeutic potential and is important for all clinicians who care for patients with HF to understand the rationale and approach to treatment.
静脉输铁羧化合物对急性心力衰竭患者与健康相关的生活质量生活质量的影响:肯定AHF研究的结果。
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发表时间: 2021-08-17
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