Differences in P300 amplitudes and topography between cycloid psychosis and schizophrenia in Leonhard's classification

Differences in P300 amplitudes and topography between cycloid psychosis and schizophrenia in Leonhard's classification
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Leonhard 分类中摆线精神病和精神分裂症 P300 振幅和地形的差异

DOI:
10.1111/j.1600-0447.1993.tb03352.x
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发表时间:
1993
影响因子:
6.7
通讯作者:
Helmut Beckmann
Helmut Beckmann
中科院分区:
医学1区
文献类型:
--
作者:
Werner Strik;Thomas Dierks;Ernst Franzek;Konrad Maurer;Helmut Beckmann

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在多重诊断方法中,我们研究了 18 名缓解型精神分裂症患者和 18 名年龄和性别匹配的对照组的听觉 P300 参数。所有患者均符合 DSM-III-R 的精神分裂症标准。应用莱昂哈德分类法,患者被细分为 7 名摆线精神病患者和 11 名莱昂哈德精神分裂症患者。摆线精神病患者符合 Brockington 等人的操作标准。我们发现莱昂哈德精神分裂症患者组的 P300 振幅显着低于对照组和摆线状精神病患者,而摆线状精神病患者和对照组之间没有显示出差异。在莱昂哈德精神分裂症组中,P300 场图的最大值和最小值都明显向右移位,但在摆线精神病组中则不然。
In a polydiagnostic approach, we investigated the parameters of auditory P300 in a group of 18 remitted schizophrenics and in 18 age‐ and sex‐matched controls. All patients fulfilled the criteria of schizophrenic disorder according to DSM‐III‐R. Applying Leonhard's classification, patients were to be subdivided into 7 cycloid psychosis and 11 Leonhard's schizophrenics. Patients with cycloid psychosis fulfilled the operational criteria of Brockington et al. We found significantly lower P300 amplitudes in the group of Leonhard's schizophrenics than in controls and in cycloid psychosis, whereas no difference could be shown between patients with cycloid psychosis and controls. Both the maxima and the minima of the P300 field map were dislocated significantly to the right in the group of Leonhard's schizophrenics but not in cycloid psychosis.
DOI: 10.1016/0013-4694(90)90083-v
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