Occupation, Worker Vulnerability, and COVID-19 Vaccination Uptake: Analysis of the Virus Watch prospective cohort study
Occupation, Worker Vulnerability, and COVID-19 Vaccination Uptake: Analysis of the Virus Watch prospective cohort study
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职业、工人脆弱性和 COVID-19 疫苗接种率：Virus Watch 前瞻性队列研究分析
DOI：
10.1101/2022.06.12.22276307
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Beale S
中科院分区：
文献类型：
--
作者：
Beale S
COVID-19疫苗接种的职业差异可能会影响疫苗接种计划的有效性，并为弱势工人和工作场所暴露高的人带来特殊风险。本研究旨在调查按职业划分的COVID-19疫苗接种情况，包括弱势群体和职业暴露状况。方法我们使用的数据来自提供职业信息的受雇或自雇成年人，作为病毒观察前瞻性队列研究的一部分（n= 19，595），并将其与研究获得的关于可移植性相关特征的信息联系起来（年龄、医疗状况、肥胖状况）及工作相关的COVID-19暴露。根据与国家记录和研究记录的联系，获得任何COVID-19疫苗第一剂、第二剂和第三剂的受试者接种状态。我们计算了按职业总体、按可接种性相关特征和按工作暴露划分的疫苗接种比例和Sison-Glaz多项式95%置信区间。服务和销售人员的吸收率一直最低。与非脆弱工人相比，脆弱工人在摄取方面的职业间差异往往较少，尽管临床脆弱的运输工人（各剂量为76%-89%）的摄取率低于其他几个职业群体（各剂量最大值为86%-96%）。SARS-CoV-2暴露风险较低的工人的疫苗接种率（86%-96%）高于高风险或高风险的工人（81%-94%）。解释不同职业的疫苗接种率，特别是在脆弱和高度暴露的工人中，可能会恶化感染结果中的职业和相关社会经济不平等。需要进一步调查影响差异摄取的职业和非职业因素，以便为未来COVID-19加强剂推广和类似疫苗接种计划提供相关干预措施。
BackgroundOccupational disparities in COVID-19 vaccine uptake can impact the effectiveness of vaccination programmes and introduce particular risk for vulnerable workers and those with high workplace exposure. This study aimed to investigate COVID-19 vaccine uptake by occupation, including for vulnerable groups and by occupational exposure status.MethodsWe used data from employed or self-employed adults who provided occupational information as part of the Virus Watch prospective cohort study (n= 19,595) and linked this to study-obtained information about vulnerability-relevant characteristics (age, medical conditions, obesity status) and work-related COVID-19 exposure based on the Job Exposure Matrix. Participant vaccination status for the first, second, and third dose of any COVID-19 vaccine was obtained based on linkage to national records and study records. We calculated proportions and Sison-Glaz multinomial 95% confidence intervals for vaccine uptake by occupation overall, by vulnerability-relevant characteristics, and by job exposure.FindingsVaccination uptake across occupations ranged from 89-96% for the first dose, 87–94% for the second dose, and 75–86% for the third dose, with transport, trade, service and sales workers persistently demonstrating the lowest uptake. Vulnerable workers tended to demonstrate fewer between-occupational differences in uptake than non-vulnerable workers, although clinically vulnerable transport workers (76%-89% across doses) had lower uptake than several other occupational groups (maximum across doses 86%–96%). Workers with low SARS-CoV-2 exposure risk had higher vaccine uptake (86%-96% across doses) than those with elevated or high risk (81–94% across doses).InterpretationDifferential vaccination uptake by occupation, particularly amongst vulnerable and highly-exposed workers, is likely to worsen occupational and related socioeconomic inequalities in infection outcomes. Further investigation into occupational and non-occupational factors influencing differential uptake is required to inform relevant interventions for future COVID-19 booster rollouts and similar vaccination programmes.
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作者：
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通讯作者：
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DOI：
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发表时间：
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作者：
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DOI：
10.1016/j.ijid.2021.11.009
发表时间：
2022-01
期刊：
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
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