Hematopoietic stem cells are pluripotent and not just "hematopoietic".
Hematopoietic stem cells are pluripotent and not just "hematopoietic".
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DOI：
10.1016/j.bcmd.2013.01.008
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发表时间：
2013-06
影响因子：
2.3
通讯作者：
Mehrotra, Meenal
中科院分区：
文献类型：
--
作者：
Ogawa, Makio;LaRue, Amanda C.;Mehrotra, Meenal
Over a decade ago, several preclinical transplantation studies suggested the striking concept of the tissue-reconstituting ability (often referred to as HSC plasticity) of hematopoietic stem cells (HSCs). While this heralded an exciting time of radically new therapies for disorders of many organs and tissues, the concept was soon mired in controversy and remained dormant for almost a decade. This commentary provides a concise review of evidence for HSC plasticity, including more recent findings based on single HSC transplantation in mouse and clinical transplantation studies. There is strong evidence for the concept that HSCs are pluripotent and are the source for the majority, if not all, of the cell types in our body. Also discussed are some biological and experimental issues that need to be considered in the future investigation of HSC plasticity.
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影响因子：
56.9
作者：
Asahara, T;Murohara, T;Isner, JM
通讯作者：
Isner, JM
DOI：
10.1007/s004290050237
发表时间：
1999-05-01
期刊：
ANATOMY AND EMBRYOLOGY
影响因子：
--
作者：
Bittner, RE;Schöfer, C;Wachtler, F
通讯作者：
Wachtler, F
影响因子：
5.2
作者：
Fujita, Jun;Mori, Mitsuharu;Fukuda, Keiichi
通讯作者：
Fukuda, Keiichi
影响因子：
15.9
作者：
Crossno, Joseph T., Jr.;Majka, Susan M.;Klemm, Dwight J.
通讯作者：
Klemm, Dwight J.
影响因子：
2.6
作者：
Abe, Takanori;Masuya, Masahiro;Ogawa, Makio
通讯作者：
Ogawa, Makio