Protein Adsorption on Functionalized Carbon Nanotubes with a Lactobionic Amide Amphiphile

Protein Adsorption on Functionalized Carbon Nanotubes with a Lactobionic Amide Amphiphile
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乳糖酰胺两亲物对功能化碳纳米管的蛋白质吸附

DOI:
10.1021/ie2011214
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发表时间:
2011-09
期刊:
Industrial & Engineering Chemistry Research
影响因子:
--
通讯作者:
Peijun Ji
Peijun Ji
中科院分区:
其他
文献类型:
--
作者:
Wei Feng;Jing Xiao;Lili Li;Peijun Ji

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合成了一种乳仿酰胺两亲分子,并将其用于多壁碳纳米管的官能化。两亲分子在多壁碳纳米管上的自组装是在乙醇/水溶液中进行的。通过紫外、拉曼、X-射线光电子能谱、X-射线衍射仪和高分辨电子显微镜对碳纳米管的官能化进行了研究。研究发现,醇可以促进两亲分子在多壁碳纳米管上的自组装,并调节两亲分子的组装数量。将溶菌酶吸附在功能化的多壁碳纳米管上。圆二色谱(CD)表明,吸附后溶菌酶的构象没有明显变化。
A lactobionic amide amphiphile was synthesized and used to functionalize multiwalled carbon nanotubes (MWNTs). The self-assembly of the amphiphile on the MWNTs was carried out in alcohol/water solutions. The functionalization of the MWNTs was investigated by means of ultraviolet, Raman, and X-ray photoelectron spectroscopies; X-ray diffraction; and high-resolution transmission electron microscopy. It was found that alcohols can promote the self-assembly of the amphiphile on MWNTs and regulate the amount of amphiphile assembled. Lysozyme was adsorbed onto functionalized MWNTs. Circular dichroism (CD) spectra revealed that the conformation of lysozyme underwent no significant alteration upon adsorption.
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