Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications.
Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications.
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DOI：
10.1016/j.lanepe.2020.100012
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Fancourt D
中科院分区：
文献类型：
--
作者：
Paul E;Steptoe A;Fancourt D
对疫苗的负面态度以及不确定或不愿接种疫苗是长期管理新冠肺炎大流行的主要障碍。我们估计了对疫苗持负面态度的四个领域的预测因子，并在英国成年人的大样本中确定了最具不确定性和不愿接种新冠肺炎疫苗的风险人群。数据来自伦敦大学学院新冠肺炎社交研究中32,361名成年人的横截面数据。普通最小二乘回归分析考察了社会人口学和新冠肺炎相关因素对四种类型的负面疫苗态度的影响：不信任疫苗益处、担心不可预见的影响、担心商业牟取暴利和偏爱自然免疫。多项回归分析了社会人口学和新冠肺炎相关因素、消极的疫苗态度和既往的疫苗行为对新冠肺炎接种的不确定性和不愿接种的影响。16%的受访者对一个或多个领域的疫苗表现出高度不信任。少数民族背景的人对疫苗接种的不信任态度更高，他们的教育水平较低，年收入较低，对新冠肺炎的了解较差，对政府制定的新冠肺炎指南的遵从性也较差。总体而言，14%的受访者表示不愿接种新冠肺炎疫苗，而23%的受访者表示不确定。新冠肺炎疫苗接种不确定性和拒绝接种的最大预测因素是低收入群体(每年1.6万英磅)，他们去年没有接种过流感疫苗，较差地遵守新冠肺炎政府的指导方针，女性，以及与孩子住在一起。在疫苗态度中，对疫苗益处的中度到高度不信任以及对未来不可预见的副作用的担忧是不确定和不愿接种新冠肺炎疫苗的最重要决定因素。在英国，对疫苗的负面态度是一个主要的公共卫生问题。对疫苗的普遍不信任以及对未来副作用的担忧将成为通过接种疫苗实现人群对新冠肺炎免疫力的障碍。公共卫生信息应针对这些关切进行调整，特别是针对妇女、少数民族和受教育程度和收入较低的人。纳菲尔德基金会[WEL/FR-000022583]，由英国研究和创新支持的跨学科精神健康网络+倡议资助的3月精神健康网络[ES/S002588/1]，以及惠康信托[221400/Z/20/Z和205407/Z/16/Z]。
Negative attitudes towards vaccines and an uncertainty or unwillingness to receive vaccinations are major barriers to managing the COVID-19 pandemic in the long-term. We estimate predictors of four domains of negative attitudes towards vaccines and identify groups most at risk of uncertainty and unwillingness to receive a COVID-19 vaccine in a large sample of UK adults. Data were cross-sectional and from 32,361 adults in the UCL COVID-19 Social Study. Ordinary least squares regression analyses examined the impact of socio-demographic and COVID-19 related factors on four types of negative vaccine attitudes: mistrust of vaccine benefit, worries about unforeseen effects, concerns about commercial profiteering, and preference for natural immunity. Multinomial regression examined the impact of socio-demographic and COVID-19 related factors, negative vaccine attitudes, and prior vaccine behaviour on uncertainty and unwillingness to be vaccinated for COVID-19. 16% of respondents displayed high levels of mistrust about vaccines across one or more domains. Distrustful attitudes towards vaccination were higher amongst individuals from ethnic minority backgrounds, with lower levels of education, lower annual income, poor knowledge of COVID-19, and poor compliance with government COVID-19 guidelines. Overall, 14% of respondents reported unwillingness to receive a vaccine for COVID-19, whilst 23% were unsure. The largest predictors of both COVID-19 vaccine uncertainty and refusal were low-income groups (< £16,000, a year), having not received a flu vaccine last year, poor adherence to COVID-19 government guidelines, female gender, and living with children. Amongst vaccine attitudes, intermediate to high levels of mistrust of vaccine benefit and concerns about future unforeseen side effects were the most important determinants of both uncertainty and unwillingness to vaccinate against COVID-19. Negative attitudes towards vaccines are a major public health concern in the UK. General mistrust in vaccines and concerns about future side effects in particular will be barriers to achieving population immunity to COVID-19 through vaccination. Public health messaging should be tailored to address these concerns and specifically to women, ethnic minorities, and people with lower levels of education and incomes. The Nuffield Foundation [WEL/FR-000022583], the MARCH Mental Health Network funded by the Cross-Disciplinary Mental Health Network Plus initiative supported by UK Research and Innovation [ES/S002588/1], and the Wellcome Trust [221400/Z/20/Z and 205407/Z/16/Z].
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影响因子：
4.6
作者：
Cacciapaglia G;Cot C;Sannino F
通讯作者：
Sannino F
影响因子：
3.8
作者：
Martin, Leslie R.;Petrie, Keith J.
通讯作者：
Petrie, Keith J.
DOI：
10.1016/s0140-6736(20)31558-0
发表时间：
2020-09-26
期刊：
Lancet (London, England)
影响因子：
--
作者：
de Figueiredo A;Simas C;Karafillakis E;Paterson P;Larson HJ
通讯作者：
Larson HJ
公众对澳大利亚共同的看法：感知的风险，知识，健康保护行为和疫苗意图。
影响因子：
3.8
作者：
Faasse K;Newby J
通讯作者：
Newby J
影响因子：
5.8
作者：
Royston, Patrick;White, Ian R.
通讯作者：
White, Ian R.