The role of interstitial fluid pressurization in articular cartilage lubrication.
The role of interstitial fluid pressurization in articular cartilage lubrication.
复制标题
DOI：
10.1016/j.jbiomech.2009.04.040
复制
发表时间：
2009-06-19
影响因子：
2.4
通讯作者：
Ateshian, Gerard A.
中科院分区：
文献类型：
--
作者：
Ateshian, Gerard A.
在过去的二十年中，软骨力学领域取得了相当大的进展，这影响了我们对间质液加压对软骨润滑作用的理解。理论和实验研究已经证明，软骨的间质液在负载下相当大地加压，可能在各种瞬态或稳态条件下支持大部分施加的负载。由流体加压支撑的总载荷的一部分被称为流体载荷支撑。实验研究表明，软骨的摩擦系数与该变量呈负相关，当流体负载支撑最大时，达到显著低的值。体现这种关系的理论框架已经过实验验证，预测和解释了各种结果，并证明了在正常生理功能下，低摩擦系数可以保持较长的负荷持续时间。本文回顾了这一主题的突出方面，以及它的影响，以提高我们的理解边界润滑的分子物种在滑液和软骨浅表区。本文还综述了软骨退变对其摩擦响应的影响。
Over the last two decades, considerable progress has been reported in the field of cartilage mechanics that impacts our understanding of the role of interstitial fluid pressurization on cartilage lubrication. Theoretical and experimental studies have demonstrated that the interstitial fluid of cartilage pressurizes considerably under loading, potentially supporting most of the applied load under various transient or steady-state conditions. The fraction of the total load supported by fluid pressurization has been called the fluid load support. Experimental studies have demonstrated that the friction coefficient of cartilage correlates negatively with this variable, achieving remarkably low values when the fluid load support is greatest. A theoretical framework that embodies this relationship has been validated against experiments, predicting and explaining various outcomes, and demonstrating that a low friction coefficient can be maintained for prolonged loading durations under normal physiological function. This paper reviews salient aspects of this topic, as well as its implications for improving our understanding of boundary lubrication by molecular species in synovial fluid and the cartilage superficial zone. Effects of cartilage degeneration on its frictional response are also reviewed.
登录
查看更多内容
DOI：
10.1115/1.3138409
发表时间：
1983-01-01
影响因子：
1.7
作者：
AHMED, AM;BURKE, DL
通讯作者：
BURKE, DL
DOI：
10.1243/095441105x69060
发表时间：
2006-01-01
影响因子：
1.8
作者：
Bell, CJ;Ingham, E;Fisher, J
通讯作者：
Fisher, J
影响因子：
6.6
作者：
BOWEN, RM
通讯作者：
BOWEN, RM
影响因子：
27.4
作者：
CHARNLEY, J
通讯作者：
CHARNLEY, J
DOI：
10.1243/0954411991535167
发表时间：
1999-01-01
影响因子：
1.8
作者：
Forster, H;Fisher, J
通讯作者：
Fisher, J