Biomechanical Loading Evaluation of Unsintered Hydroxyapatite/poly-l-lactide Plate System in Bilateral Sagittal Split Ramus Osteotomy.
Biomechanical Loading Evaluation of Unsintered Hydroxyapatite/poly-l-lactide Plate System in Bilateral Sagittal Split Ramus Osteotomy.
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DOI：
10.3390/ma10070764
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发表时间：
2017-07-07
期刊：
影响因子：
--
通讯作者：
Furuki Y
中科院分区：
文献类型：
--
作者：
Sukegawa S;Kanno T;Manabe Y;Matsumoto K;Sukegawa-Takahashi Y;Masui M;Furuki Y
OSTEOTRANS MX®（Takiron Co.，有限公司、Osaka，Japan）是一种生物活性可吸收颌面骨合成材料，由未烧结的羟基磷灰石/聚-L-丙交酯复合材料组成，其有效的骨传导能力先前已被记录。然而，该接骨板系统的机械强度尚不清楚。因此，本体外研究的目的是通过模拟临床环境中的咀嚼力，评估其拉伸和剪切强度，并评价不同接骨板设计在升支矢状劈开截骨术后的生物力学强度。对于拉伸和剪切强度分析，通过将未烧结的羟基磷灰石/聚-L-丙交酯组成的板固定到聚碳酸酯骨骼模型来制备三个机械强度测量样品。在生物力学载荷评估方面，使用12个下颌骨复制品，并将其分为四组进行下颌升支矢状劈开截骨术固定。将每个样品固定在夹具中，并在第一磨牙上经受垂直载荷。关于剪切强度，新型未烧结羟基磷灰石/聚-L-丙交酯接骨板具有显著高强度。在生物力学载荷评价时，该接骨板系统除生物活性外还显示出显著的高稳定性，未观察到接骨板断裂。因此，我们已经使用下颌骨双侧升支矢状劈开截骨术的体外模型清楚地证明了该接骨板系统的有效性。
OSTEOTRANS MX® (Takiron Co., Ltd., Osaka, Japan) is a bioactive resorbable maxillofacial osteosynthetic material composed of an unsintered hydroxyapatite/poly-l-lactide composite, and its effective osteoconductive capacity has been previously documented. However, the mechanical strength of this plate system is unclear. Thus, the aim of this in vitro study was to assess its tensile and shear strength and evaluate the biomechanical intensity of different osteosynthesis plate designs after sagittal split ramus osteotomy by simulating masticatory forces in a clinical setting. For tensile and shear strength analyses, three mechanical strength measurement samples were prepared by fixing unsintered hydroxyapatite/poly-l-lactide composed plates to polycarbonate skeletal models. Regarding biomechanical loading evaluation, 12 mandibular replicas were used and divided into four groups for sagittal split ramus osteotomy fixation. Each sample was secured in a jig and subjected to vertical load on the first molar teeth. Regarding shear strength, the novel-shaped unsintered hydroxyapatite/poly-l-lactide plate had significantly high intensity. Upon biomechanical loading evaluation, this plate system also displayed significantly high stability in addition to bioactivity, with no observed plate fracture. Thus, we have clearly demonstrated the efficacy of this plate system using an in vitro model of bilateral sagittal split ramus osteotomy of the mandible.
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影响因子：
1.9
作者：
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期刊：
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影响因子：
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作者：
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通讯作者：
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