Job strain and cognitive change: the Baltimore Epidemiologic Catchment Area follow-up study.

Job strain and cognitive change: the Baltimore Epidemiologic Catchment Area follow-up study.
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工作压力和认知变化:巴尔的摩流行病学区域随访研究。

DOI:
10.1136/oemed-2018-105213
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发表时间:
2018-12
影响因子:
4.9
通讯作者:
Mojtabai R
Mojtabai R
中科院分区:
医学2区
文献类型:
--
作者:
Dong L;Eaton WW;Spira AP;Agnew J;Surkan PJ;Mojtabai R

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使用基于人群的巴尔的摩流行病学流域地区随访研究的数据,调查工作压力与随后约11年认知变化之间的关联。样本范围从555到563名参与者,根据结果,他们报告了与基线(1993-1996年)全职工作相对应的心理社会特征。在基线和随访(2003-2004年)时,通过简易精神状态检查(MMSE)测量总体认知表现,通过即时和延迟单词回忆任务(IWRT和DWRT)测量言语记忆。多元线性回归被用来研究工作紧张和认知变化之间的联系,并使用逆概率加权来解释差异性减员。高工作要求(心理或身体要求)和/或低工作控制的被试比低工作要求和高工作控制的被试在MMSE和记忆分数上有更大的下降。在对基线结果评分、年龄和性别进行调整后,在工作要求高、工作控制低的参与者中观察到最大的下降(MMSE:-0.24,95%置信区间[CI]:-0.36,-0.11;言语记忆评分:-0.26,95% CI:-0.44,-0.07)。社会人口学特征、职业声望和健康因素部分解释了这些差异。这项前瞻性研究的结果表明,工作压力与不良认知结果相关,并且可能是一个潜在的可改变的风险因素。
To investigate the association between job strain and subsequent cognitive change over approximately 11 years, using data from the population-based Baltimore Epidemiologic Catchment Area Follow-up Study. The sample ranged from 555 to 563 participants, depending on the outcome, who reported psychosocial characteristics corresponding to the full-time job they held at baseline (1993–1996). Overall cognitive performance was measured by the Mini-Mental State Examination (MMSE), and verbal memory was measured by the Immediate and Delayed Word Recall Tasks (IWRT and DWRT) at baseline and follow-up (2003–2004). Multiple linear regression was used to examine the association between job strain and cognitive change, and inverse probability weighting was used to account for differential attrition. Participants with high job demands (psychological or physical demands) and/or low job control had greater decrease in the MMSE and memory scores than those with low job demands and high job control. After adjustment for baseline outcome scores, age and sex, the greatest decrease was observed in participants with high job demands and low job control (MMSE: −0.24, 95% confidence interval [CI]: −0.36, −0.11; verbal memory scores: −0.26, 95% CI: −0.44, −0.07). The differences were partially explained by sociodemographic characteristics, occupational prestige and health factors. Findings from this prospective study suggest that job strain is associated with, and may be a potential modifiable risk factor for adverse cognitive outcomes.
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