Cellular fatty acid metabolism and cancer.
Cellular fatty acid metabolism and cancer.
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DOI:
10.1016/j.cmet.2013.05.017
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发表时间:
2013-08-06
期刊:
影响因子:
29
通讯作者:
Farese RV Jr
中科院分区:
文献类型:
--
作者:
Currie E;Schulze A;Zechner R;Walther TC;Farese RV Jr
Cancer cells commonly have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.
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