Comparison of Prevalence and Outcomes of Pediatric Acute Respiratory Distress Syndrome Using Pediatric Acute Lung Injury Consensus Conference Criteria and Berlin Definition.
Comparison of Prevalence and Outcomes of Pediatric Acute Respiratory Distress Syndrome Using Pediatric Acute Lung Injury Consensus Conference Criteria and Berlin Definition.
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DOI：
10.3389/fped.2018.00093
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发表时间：
2018
影响因子：
2.6
通讯作者：
Kabra SK
中科院分区：
文献类型：
--
作者：
Gupta S;Sankar J;Lodha R;Kabra SK
我们的目的是使用儿科急性肺损伤共识会议（PALICC）标准和柏林定义比较儿科急性呼吸窘迫综合征的患病率和结局。我们筛选了3年（2015-2017年）期间（2015-2017年）入住儿科重症监护室（PICU）的所有1个月至17岁儿童的病例记录，以确定入院时或PICU住院期间是否存在任何呼吸困难。我们对这些患者应用了PALICC和柏林标准。数据收集包括定义和结局相关变量。使用Stata 11比较“仅行PALICC组”和“行或不行PALICC的柏林”组之间的数据。在总共615名住院患者中，246名在入院时或PICU住院期间被确定为呼吸困难。共有61名儿童（患病率为9.9%; 95%CI：7.8-12.4）符合急性呼吸窘迫综合征（ARDS）的定义与两个标准之一。60名儿童（98%）符合PALICC标准，只有26名儿童（43%）符合柏林定义。两种定义之间存在中度一致性（Kappa：0.51; 95% CI：0.40-0.62;观察到的一致性为85%）。“柏林联合或不联合PALICC组”中重度ARDS患者比例高于“仅PALICC组”（50 vs. 19%）。两组在关键临床结局方面无差异，如通气持续时间（7天vs. 8天）或死亡率[51. 4 vs. 57. 7%：RR（95% CI）：0. 99（0. 64 - 1. 5）]。与柏林标准相比，PALICC标准确定了更多的ARDS患者。“柏林联合或不联合PALICC”组中重度ARDS和并发症的比例高于“仅PALICC”组。两组之间的临床结局无差异。
Our objective was to compare the prevalence and outcomes of pediatric acute respiratory distress syndrome using the Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria and Berlin definitions. We screened case records of all children aged 1 month to 17 years of age admitted to the Pediatric Intensive Care Unit (PICU) over a 3-year period (2015–2017) for presence of any respiratory difficulty at admission or during PICU stay. We applied both PALICC and Berlin criteria to these patients. Data collection included definition and outcome related variables. Data were compared between the “PALICC only group” and the “Berlin with or without PALICC” group using Stata 11. Of a total of 615 admissions, 246 were identified as having respiratory difficulty at admission or during PICU stay. A total of 61 children (prevalence 9.9%; 95% CI: 7.8–12.4) fulfilled the definition of acute respiratory distress syndrome (ARDS) with either of the two criteria. While 60 children (98%) fulfilled PALICC criteria, only 26 children (43%) fulfilled Berlin definition. There was moderate agreement between the two definitions (Kappa: 0.51; 95% CI: 0.40–0.62; observed agreement 85%). Greater proportion of patients had severe ARDS in the “Berlin with or without PALICC group” as compared to the “PALICC only” group (50 vs. 19%). There was no difference between the groups with regard to key clinical outcomes such as duration of ventilation (7 vs. 8 days) or mortality [51.4 vs. 57.7%: RR (95% CI): 0.99 (0.64–1.5)]. In comparison to Berlin definition, the PALICC criteria identified more number of patients with ARDS. Proportion with severe ARDS and complications was greater in the “Berlin with or without PALICC” group as compared to the “PALICC only” group. There were no differences in clinical outcomes between the groups.
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DOI：
10.1164/rccm.200112-117oc
发表时间：
2002-08-01
影响因子：
24.7
作者：
Sinclair, SE;Kregenow, DA;Hlastala, MP
通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
38.9
作者：
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通讯作者：
Kneyber, Martin
影响因子：
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作者：
Rotta AT;Piva JP;Andreolio C;de Carvalho WB;Garcia PC
通讯作者：
Garcia PC