Immune Microenvironment: New Insight for Familial Adenomatous Polyposis.
Immune Microenvironment: New Insight for Familial Adenomatous Polyposis.
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免疫微环境:家族性腺瘤性息肉病的新见解
DOI:
10.3389/fonc.2021.570241
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发表时间:
2021
影响因子:
4.7
通讯作者:
Zhang H
中科院分区:
文献类型:
--
作者:
Yang J;Wen Z;Li W;Sun X;Ma J;She X;Zhang H;Tu C;Wang G;Huang D;Shen X;Dong J;Zhang H
Currently, the main treatment for familial adenomatous polyposis (FAP) is surgery, however, surgery is far from ideal as there are many complications such as uncontrollable bowel movements, pouch inflammation, anastomotic stricture, and secondary fibroids. Therefore, it is necessary to further expand the understanding of FAP and develop new treatments for FAP. The immune microenvironment including immune cells and cytokines, plays an important role in FAP and the progression of FAP to adenocarcinoma, thus it may be a promising treatment for FAP. In the current review, we summarized the recent progress in the immune microenvironment of FAP.
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影响因子:
10.1
作者:
通讯作者:
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影响因子:
24.5
作者:
Betts G;Jones E;Junaid S;El-Shanawany T;Scurr M;Mizen P;Kumar M;Jones S;Rees B;Williams G;Gallimore A;Godkin A
通讯作者:
Godkin A
影响因子:
8.7
作者:
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通讯作者:
Dinarello CA
影响因子:
7.3
作者:
Chapple, KS;Scott, N;Hull, MA
通讯作者:
Hull, MA
影响因子:
4.7
作者:
BeazerBarclay, Y;Levy, DB;Kinzler, KW
通讯作者:
Kinzler, KW