Electrophysiology as a prognostic indicator of visual recovery in diabetic patients undergoing cataract surgery.
Electrophysiology as a prognostic indicator of visual recovery in diabetic patients undergoing cataract surgery.
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DOI：
10.1007/s00417-021-05100-8
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Li S
中科院分区：
文献类型：
--
作者：
Wang H;Li F;Li J;Lin J;Liu M;Wang G;Wang M;Ran L;Robson AG;Li S
患有视网膜或视觉通路疾病的糖尿病患者白内障手术后的视力结果很难预测，因为眼底可能会被遮挡，并且视觉潜力的评估具有挑战性。本研究评估了视觉电生理学作为糖尿病白内障患者在白内障手术前视力恢复的预后指标的价值。 41 名糖尿病患者（年龄 52-80 岁；74 只眼睛）和 13 名年龄匹配的非糖尿病对照患者（21 只眼睛）在白内障手术前接受了检查。术前检查包括最佳矫正视力 (BCVA)、裂隙灯生物显微镜、ISCEV 标准全视野视网膜电图 (ffERG) 和闪光视觉诱发电位 (闪光 VEP) 测试。电生理学评估包括 DA 和 LA ERG、振荡电位（OP；OP1、OP2、OP3、OP4）和闪光 VEP P1、P2 和 P3 分量的量化。对所有病例进行术后BCVA测量，并根据视力丧失的严重程度对糖尿病患者进行分组：轻度（logMAR ≤ 0.1）、中度（0.1 < logMAR < 0.5）或重度（logMAR ≥ 0.5）。第四组包括那些没有糖尿病的人。通过方差分析比较四组之间的术前电生理数据。糖尿病患者术后视力丧失的严重程度分为轻度（N=22 只眼）、中度（N=31 只眼）或重度（N=21 只眼）。在没有糖尿病的组中，术后视力障碍被归类为轻度（N = 21 只眼睛）。术前 DA 10.0 ERG a 波振幅、DA 3.0 ERG OP2 振幅以及 LA 3.0 a 和 b 波振幅在四组中显示出最显着的差异。闪光视觉诱发电位（Flash VEP）在组间没有显示出显着差异。对患有白内障的糖尿病患者进行电生理学评估可以提供视网膜功能的有用测量。全视野 ERG 分量，包括 DA 10.0 ERG a 波、DA 3.0 ERG OP2 分量以及 LA 3.0 a 和 b 波振幅，对于预测术后视力具有预后价值，并且可以为糖尿病白内障患者的手术治疗提供参考。在线版本包含可在 10.1007/s00417-021-05100-8 获取的补充材料。
Visual outcomes after cataract surgery in diabetic patients with retinal or visual pathway disease are difficult to predict as the fundus may be obscured, and assessment of visual potential is challenging. This study assessed the value of visual electrophysiology as a prognostic indicator of visual recovery in diabetic patients with cataract, prior to cataract surgery. Forty-one diabetic patients (aged 52–80; 74 eyes) and 13 age-matched non-diabetic control patients (21 eyes) were examined prior to cataract surgery. Pre-surgical examinations included best-corrected visual acuity (BCVA), slit-lamp bio-microscopy, ISCEV-standard full-field electroretinography (ffERG), and flash visual evoked potential (flash VEP) testing. Electrophysiological assessments included quantification of the DA and LA ERG, oscillatory potentials (OPs; OP1, OP2, OP3, OP4) and flash VEP P1, P2, and P3 components. Post-operative BCVA was measured in all cases and the diabetic patients grouped according to the severity of visual acuity loss: mild (logMAR ≤ 0.1), moderate (0.1 < logMAR < 0.5), or severe (logMAR ≥ 0.5). A fourth group included those without diabetes. The pre-surgical electrophysiological data was compared between the four groups by analysis of variance. The severity of post-surgical visual acuity loss in the diabetic patients was classified as mild (N=22 eyes), moderate (N=31 eyes), or severe (N=21 eyes). In the group without diabetes, post-surgical visual impairment was classified as mild (N=21 eyes). The pre-operative DA 10.0 ERG a-wave amplitudes, DA 3.0 ERG OP2 amplitudes, and the LA 3.0 a- and b-wave amplitudes showed best significant differences among the four groups. The flash VEP did not show significant difference between groups. Electrophysiological assessment of diabetic patients with cataract can provide a useful measure of retinal function. Full-field ERG components, including the DA 10.0 ERG a-wave, DA 3.0 ERG OP2 component, and the LA 3.0 a- and b-wave amplitudes, are of prognostic value in predicting post-surgical visual acuity, and may inform the surgical management of cataract patients with diabetes. The online version contains supplementary material available at 10.1007/s00417-021-05100-8.
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影响因子：
3.4
作者：
Kim, Mirinae;Kim, Rae-Young;Park, Young-Hoon
通讯作者：
Park, Young-Hoon
DOI：
10.1007/s00417-002-0530-7
发表时间：
2002-09-01
影响因子：
2.7
作者：
Krepler, K;Biowski, R;Wedrich, A
通讯作者：
Wedrich, A
影响因子：
2.2
作者：
Yamauchi, Yasuyuki;Mochizuki, Jun-ichi;Uda, Shigekazu
通讯作者：
Uda, Shigekazu
影响因子：
3
作者：
Lin D;Chen J;Liu Z;Lin Z;Li X;Wu X;Cao Q;Lin H;Chen W;Liu Y
通讯作者：
Liu Y
影响因子：
1.4
作者：
Wördehoff, UV;Palmowski, AM;Ruprecht, KW
通讯作者：
Ruprecht, KW