Impairments of Visual Function and Ocular Structure in Patients With Unilateral Posterior Lens Opacity.
Impairments of Visual Function and Ocular Structure in Patients With Unilateral Posterior Lens Opacity.
复制标题
DOI：
10.1167/tvst.7.4.9
复制
发表时间：
2018-07
影响因子：
3
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Lin D;Chen J;Liu Z;Lin Z;Li X;Wu X;Cao Q;Lin H;Chen W;Liu Y
我们研究了单侧后透镜混浊患者的视功能损害和眼结构，这是我们新的先天性白内障分类系统中的一种类型。我们研究了3至15岁的患者，他们被诊断为单侧后部CC。检查最佳矫正视力（BCVA）和视觉诱发电位（VEP）。采用Pentacam和IOL-Master测量角膜散光（CA）、平均角膜曲率、中央角膜厚度、前房深度（ACD）和眼轴长度。通过配对t检验比较双眼之间的变化。在25例患者中，白内障眼和对侧健康眼的BCVA（logMAR）分别为0.8 ± 0.4（范围：0.1-1.7）和0.1 ± 0.1（范围：-0.1至0.4）。与对侧健康眼相比，白内障患者的CA更大（1.8 ± 1.2 vs. 0.9 ± 0.4屈光度[D]，P = 0.002），ACD更深（3.7 ± 0.3 vs. 3.5 ± 0.4 mm，P = 0.009）。BCVA与VEP各参数之间无显著的正相关或负相关。白内障组VEP-60′波P100峰值时间（114.9 ± 18.8）ms较健侧（105.0 ± 12.4）ms明显延长（P = 0.013）。白内障患者VEP-60′和-15′的P100波幅均小于对侧健康眼（PVEP-60′，15.2 ± 5.3 vs.19.9 ± 10.4 μV，P = 0.023; PVEP-15′，10.4 ± 7.0 vs.22.1 ± 11.9 μV，P = 0.012）。后透镜混浊患者的视觉功能和眼部结构受损。本研究为有争议的单侧后路CC患者的治疗方案提供了循证临床建议。
We investigate visual function impairment and ocular structure in patients with unilateral posterior lens opacity, a type of congenital cataract (CC) in our novel CC category system. We studied patients aged 3 to 15 years who were diagnosed with unilateral posterior CC. Best corrected visual acuity (BCVA) and visual evoked potentials (VEP) were examined. Corneal astigmatism (CA), mean keratometry, central corneal thickness, anterior chamber depth (ACD), and axial length were measured by Pentacam and IOL-Master. Variations between two eyes were compared by paired t-tests. Among the 25 patients involved, BCVAs (logMAR) of cataractous and contralateral healthy eyes were 0.8 ± 0.4 (range, 0.1–1.7) and 0.1 ± 0.1 (range, −0.1 to 0.4). Compared to contralateral healthy eyes, larger CA (1.8 ± 1.2 vs. 0.9 ± 0.4 diopters [D], P = 0.002) and deeper ACD (3.7 ± 0.3 vs. 3.5 ± 0.4 mm, P = 0.009) were found in cataractous eyes. No significant positive or negative linear relationship was found between BCVA and parameters of VEP. Peak time of P100 of pattern VEP-60′ in cataractous eyes was longer than that in contralateral healthy eyes (114.9 ± 18.8 vs. 105.0 ± 12.4 ms, P = 0.013). Amplitudes of P100 of patterns VEP-60′ and -15′ in cataractous eyes were smaller than those in contralateral healthy eyes (PVEP-60′, 15.2 ± 5.3 vs. 19.9 ± 10.4 μV, P = 0.023; PVEP-15′, 10.4 ± 7.0 vs. 22.1 ± 11.9 μV, P = 0.012). Impaired visual function and ocular structure were detected in patients with posterior lens opacities. This study provides evidence-based clinical recommendations for unilateral posterior CC patients with controversial treatment options.
登录
查看更多内容
影响因子：
3.7
作者：
Lin D;Chen J;Lin Z;Li X;Wu X;Long E;Luo L;Zhang B;Chen H;Chen W;Zhang L;Lin H;Chen W;Liu Y
通讯作者：
Liu Y
影响因子：
3.7
作者：
Lin HX;Qiu HJ;Zeng F;Rao HL;Yang GF;Kung HF;Zhu XF;Zeng YX;Cai MY;Xie D
通讯作者：
Xie D
中国先天性白内障患者术前角膜散光患病率及眼前节生物测量特征
影响因子：
4.6
作者：
Lin D;Chen J;Liu Z;Wu X;Long E;Luo L;Lin Z;Li X;Zhang L;Chen H;Liu J;Chen W;Lin H;Liu Y
通讯作者：
Liu Y
DOI：
10.1007/s00417-014-2728-x
发表时间：
2014-11-01
影响因子：
2.7
作者：
Fuest, Matthias;Plange, Niklas;Mazinani, Babac
通讯作者：
Mazinani, Babac
影响因子：
1.7
作者：
Mahajan, Yatin;McArthur, Genevieve
通讯作者：
McArthur, Genevieve