A cross-sectional survey of potential factors, motivations, and barriers influencing research participation and retention among people who use drugs in the rural USA.
A cross-sectional survey of potential factors, motivations, and barriers influencing research participation and retention among people who use drugs in the rural USA.
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DOI：
10.1186/s13063-021-05919-w
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发表时间：
2021-12-20
期刊：
影响因子：
2.5
通讯作者：
Lancaster KE
中科院分区：
文献类型：
--
作者：
Hetrick AT;Young AM;Elman MR;Bielavitz S;Alexander RL;Brown M;Waddell EN;Korthuis PT;Lancaster KE
尽管美国农村吸毒者(PWUD)的发病率和死亡率很高，但大多数研究都是在城市地区进行的。我们的目标是描述农村残障人士参与和保留研究的影响因素、动机和障碍。2019年4月至7月，我们从社区外展和基于社区的流行病学研究队列中招募了255名符合条件的参与者参加横断面调查。符合条件的参与者报告说，阿片类药物或注射药物的使用在30 天内达到高潮，并居住在俄勒冈州、肯塔基州和俄亥俄州的高需求农村县。我们汇总了回应排名，以确定显著的影响、动机和障碍。我们使用对数二项模型估计患病率，以评估性别、首选药物使用和地理差异。大多数参与者是男性(55%)，比起海洛因(35%)，他们更喜欢甲基苯丙胺(36%)。参与者报告的机密性、经济补偿金额和所需时间是参与研究的主要影响因素。参与的主要动机包括经济补偿、免费的艾滋病毒/丙型肝炎病毒检测和对研究的贡献。更改或错误的参与者联系信息和交通工具是留住员工的主要障碍。与海洛因相比，更喜欢冰毒的受访者报告了他们信息的目的和使用的影响(PR=1.12；95%CI：1.00，1.26)。女性和俄勒冈州人(与阿巴拉契亚人相比)报告知道并希望帮助研究团队是参与动机(PR=1.57；95%CI：1.09，2.26和PR=2.12；95%CI：1.51，2.99)。除了经济补偿外，研究人员还应强调保密，提供检测并与护理挂钩，使用多种联系方式，帮助运输，并适应人口统计差异，以提高农村PWUD的研究参与度和保留率。网上版载有补充材料，可在10.1186/s13063-021-05919-w查阅。
Despite high morbidity and mortality among people who use drugs (PWUD) in rural America, most research is conducted within urban areas. Our objective was to describe influencing factors, motivations, and barriers to research participation and retention among rural PWUD. We recruited 255 eligible participants from community outreach and community-based, epidemiologic research cohorts from April to July 2019 to participate in a cross-sectional survey. Eligible participants reported opioid or injection drug use to get high within 30 days and resided in high-needs rural counties in Oregon, Kentucky, and Ohio. We aggregated response rankings to identify salient influences, motivations, and barriers. We estimated prevalence ratios to assess for gender, preferred drug use, and geographic differences using log-binomial models. Most participants were male (55%) and preferred methamphetamine (36%) over heroin (35%). Participants reported confidentiality, amount of financial compensation, and time required as primary influential factors for research participation. Primary motivations for participation include financial compensation, free HIV/HCV testing, and contribution to research. Changed or false participant contact information and transportation are principal barriers to retention. Respondents who prefer methamphetamines over heroin reported being influenced by the purpose and use of their information (PR = 1.12; 95% CI: 1.00, 1.26). Females and Oregonians (versus Appalachians) reported knowing and wanting to help the research team as participation motivation (PR = 1.57; 95% CI: 1.09, 2.26 and PR = 2.12; 95% CI: 1.51, 2.99). Beyond financial compensation, researchers should emphasize confidentiality, offer testing and linkage with care, use several contact methods, aid transportation, and accommodate demographic differences to improve research participation and retention among rural PWUD. The online version contains supplementary material available at 10.1186/s13063-021-05919-w.
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