Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS

Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS
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UPLC-MS 半定量测定血浆中银杏内酯 B 的单羧酸盐形式

DOI:
10.1007/s00216-015-8628-z
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发表时间:
2015-03
影响因子:
4.3
通讯作者:
Ke Lan
Ke Lan
中科院分区:
化学2区
文献类型:
--
作者:
Xue Fan;Ling Wang;Kui Yang;Ke Lan

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银杏内酯B(GB)具有独特的结构,含有三个γ-内酯,在水中可水解为羧酸盐形式。然而,由于没有办法制备任何水解产物的标准品,因此它们的测定具有挑战性
AbstractGinkgolide B (GB) has a unique structure incorporating three γ-lactones that may be hydrolyzed in aquae as carboxylate forms. However, the determinations of them are challenging because there is no way to prepare the standards of any hydrolyzed pr
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