Plasmodium infection, anaemia and mosquito net use among school children across different settings in Kenya.
Plasmodium infection, anaemia and mosquito net use among school children across different settings in Kenya.
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DOI：
10.1111/j.1365-3156.2012.03001.x
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发表时间：
2012-07
期刊：
影响因子：
--
通讯作者：
Brooker SJ
中科院分区：
文献类型：
--
作者：
Gitonga CW;Edwards T;Karanja PN;Noor AM;Snow RW;Brooker SJ
调查学校儿童中疟原虫感染和贫血的风险因素，包括报告的蚊帐使用情况，并探讨肯尼亚发生的不同疟疾生态的影响差异。这项研究分析了2008-2010年全国学校疟疾调查期间接受调查的480所学校的49 975名学童的数据。采用混合效应Logistic回归分析方法，对不同疟疾传播区的疟疾感染和贫血的相关因素进行了研究。在沿海和西部高地流行区以及湖滨高传播区的男孩中，使用驱虫蚊帐与降低疟原虫感染几率有关。疟疾感染和贫血的其他风险因素也因地区而异。在所有传播环境中，疟原虫感染与社会经济地位的提高呈负相关，但在半干旱的东北地区除外。在湖滨高传播区、西部高地流行区和中部低风险区，疟原虫感染是贫血症的一个危险因素，而驱虫蚊帐的使用仅与沿海和中部地区以及湖滨高传播区男孩的贫血症发病率较低有关。在肯尼亚，疟原虫感染和贫血的风险因素，包括与使用驱虫蚊帐的保护性联系，因疟疾传播环境而异，今后控制疟疾和贫血的努力应考虑到学童中的这种异质性。
To investigate risk factors, including reported net use, for Plasmodium infection and anaemia among school children and to explore variations in effects across different malaria ecologies occurring in Kenya. This study analysed data for 49 975 school children in 480 schools surveyed during a national school malaria survey, 2008–2010. Mixed effects logistic regression was used to investigate factors associated with Plasmodium infection and anaemia within different malaria transmission zones. Insecticide-treated net (ITN) use was associated with reduction in the odds of Plasmodium infection in coastal and western highlands epidemic zones and among boys in the lakeside high transmission zone. Other risk factors for Plasmodium infection and for anaemia also varied by zone. Plasmodium infection was negatively associated with increasing socio-economic status in all transmission settings, except in the semi-arid north-east zone. Plasmodium infection was a risk factor for anaemia in lakeside high transmission, western highlands epidemic and central low-risk zones, whereas ITN use was only associated with lower levels of anaemia in coastal and central zones and among boys in the lakeside high transmission zone. The risk factors for Plasmodium infection and anaemia, including the protective associations with ITN use, vary according to malaria transmission settings in Kenya, and future efforts to control malaria and anaemia should take into account such heterogeneities among school children.
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影响因子：
6.4
作者：
Brooker, Simon J.;Pullan, Rachel L.;Snow, Robert W.
通讯作者：
Snow, Robert W.
影响因子：
3.3
作者：
Barger, Breanna;Maiga, Hamma;Djimde, Abdoulaye A.
通讯作者：
Djimde, Abdoulaye A.
影响因子：
3
作者：
Hightower, Allen;Kiptui, Rebecca;Akhwale, Willis
通讯作者：
Akhwale, Willis
DOI：
10.4269/ajtmh.2003.68.86
发表时间：
2003-04-01
影响因子：
3.3
作者：
Leenstra, T;Phillips-Howard, PA;ter Kuile, FO
通讯作者：
ter Kuile, FO
影响因子：
4
作者：
Koukounari, Artemis;Estambale, Benson B. A.;Brooker, Simon
通讯作者：
Brooker, Simon