Four-dimensional flow cardiovascular magnetic resonance in tetralogy of Fallot: a systematic review.
Four-dimensional flow cardiovascular magnetic resonance in tetralogy of Fallot: a systematic review.
复制标题
DOI：
10.1186/s12968-021-00745-0
复制
发表时间：
2021-05-20
期刊：
影响因子：
--
通讯作者：
Young AA
中科院分区：
文献类型：
--
作者：
Elsayed A;Gilbert K;Scadeng M;Cowan BR;Pushparajah K;Young AA
法洛四联症（rTOF）修复后的患者通常会发生心血管功能障碍，需要定期进行成像以评估恶化情况，并及时进行干预，如肺动脉瓣置换术。四维血流心血管磁共振（4D flow CMR）能够详细评估所有腔室和大血管中的血流特征。我们对rTOF患者的心内4D血流应用进行了系统综述，以检查临床效用并强调评价rTOF患者的最佳方法。于2020年3月在Google Scholar和Scopus上进行了全面的文献检索。一个修改后的版本的关键评估技能计划（CASP）工具，用于评估和评分的适用性，每项研究。评估了重要的临床结局，包括相似性和差异性。在识别的635篇文章中，26项研究符合系统综述的资格。这些都不低于59%的适用性，对修改后的CASP评分。研究可大致分为四类：（一）试点研究，（二）开发新的采集方法，（三）验证和（六）识别新的流动特征。与其他模式的定量比较包括2D相位对比CMR（13项研究）和超声心动图（4项研究）。4D血流研究应用包括每搏输出量（18/26;69%），洗脱剂部分（16/26;62%），相对分支肺动脉血流（4/26;15%），收缩期峰值流速（9/26;35%）、体/肺总流量比（6/26;23%）、舒张末期和收缩末期容积（5/26;19%）、动能（5/26;19%）和涡度（2/26;8%）。4D血流CMR显示出在rTOF评估中的潜力，特别是在回顾性瓣膜跟踪中用于血流评价、速度分析、心内动能定量和涡流可视化。协议应针对病理学。需要前瞻性、随机、多中心研究来验证这些新特征并确定其临床用途。
Patients with repaired Tetralogy of Fallot (rTOF) often develop cardiovascular dysfunction and require regular imaging to evaluate deterioration and time interventions such as pulmonary valve replacement. Four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) enables detailed assessment of flow characteristics in all chambers and great vessels. We performed a systematic review of intra-cardiac 4D flow applications in rTOF patients, to examine clinical utility and highlight optimal methods for evaluating rTOF patients. A comprehensive literature search was undertaken in March 2020 on Google Scholar and Scopus. A modified version of the Critical Appraisal Skills Programme (CASP) tool was used to assess and score the applicability of each study. Important clinical outcomes were assessed including similarities and differences. Of the 635 articles identified, 26 studies met eligibility for systematic review. None of these were below 59% applicability on the modified CASP score. Studies could be broadly classified into four groups: (i) pilot studies, (ii) development of new acquisition methods, (iii) validation and (vi) identification of novel flow features. Quantitative comparison with other modalities included 2D phase contrast CMR (13 studies) and echocardiography (4 studies). The 4D flow study applications included stroke volume (18/26;69%), regurgitant fraction (16/26;62%), relative branch pulmonary artery flow(4/26;15%), systolic peak velocity (9/26;35%), systemic/pulmonary total flow ratio (6/26;23%), end diastolic and end systolic volume (5/26;19%), kinetic energy (5/26;19%) and vorticity (2/26;8%). 4D flow CMR shows potential in rTOF assessment, particularly in retrospective valve tracking for flow evaluation, velocity profiling, intra-cardiac kinetic energy quantification, and vortex visualization. Protocols should be targeted to pathology. Prospective, randomized, multi-centered studies are required to validate these new characteristics and establish their clinical use.
登录
查看更多内容
DOI：
10.1002/jmri.25180
发表时间：
2016-08
期刊：
Journal of magnetic resonance imaging : JMRI
影响因子：
--
作者：
Hanneman K;Kino A;Cheng JY;Alley MT;Vasanawala SS
通讯作者：
Vasanawala SS
影响因子：
5.9
作者：
Hirtler D;Garcia J;Barker AJ;Geiger J
通讯作者：
Geiger J
影响因子：
6.4
作者：
Driessen, Mieke M. P.;Schings, Marjolijn A.;Leiner, Tim
通讯作者：
Leiner, Tim
影响因子：
14
作者：
Hope, Michael D.;Hope, Thomas A.;Higgins, Charles B.
通讯作者：
Higgins, Charles B.
影响因子：
3.3
作者：
Arvidsson, Per M.;Toger, Johannes;Arheden, Hakan
通讯作者：
Arheden, Hakan