Cortical neural dynamics unveil the rhythm of natural visual behavior in marmosets.
Cortical neural dynamics unveil the rhythm of natural visual behavior in marmosets.
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DOI：
10.1038/s42003-022-03052-1
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发表时间：
2022-02-03
影响因子：
5.9
通讯作者：
Okano H
中科院分区：
文献类型：
--
作者：
Kaneko T;Komatsu M;Yamamori T;Ichinohe N;Okano H
许多研究表明，视觉系统由功能不同的腹侧流和背侧流组成;然而，其在自然视觉行为中的确切时空动力学仍有待研究。在这里，我们报告大脑神经动力学在积极的视觉探索记录覆盖整个侧面的绒猴皮层的皮层电图阵列。我们发现，背侧流的激活先于初级视皮层的眼跳，随后腹侧流的抑制和激活信号沿着改变。同样，从背侧视觉区传播到腹侧视觉区的信号伴随着低频振荡的行波。这种信号动态发生在扫视后平均220 ms，这对应于全脑激活返回到背景水平的时间。我们还证明了扫视可以发生在信号流的任何点，表明运动指令的并行计算。总的来说，这项研究揭示了主动视觉的神经动力学，这与视觉探索的自然节奏有效地联系在一起。覆盖绒猴整个大脑皮层的ECoG阵列揭示了视觉系统的神经动力学;背侧和腹侧流在扫视后相继激活，构成了自然视觉行为的节奏。
Numerous studies have shown that the visual system consists of functionally distinct ventral and dorsal streams; however, its exact spatial-temporal dynamics during natural visual behavior remain to be investigated. Here, we report cerebral neural dynamics during active visual exploration recorded by an electrocorticographic array covering the entire lateral surface of the marmoset cortex. We found that the dorsal stream was activated before the primary visual cortex with saccades and followed by the alteration of suppression and activation signals along the ventral stream. Similarly, the signal that propagated from the dorsal to ventral visual areas was accompanied by a travelling wave of low frequency oscillations. Such signal dynamics occurred at an average of 220 ms after saccades, which corresponded to the timing when whole-brain activation returned to background levels. We also demonstrated that saccades could occur at any point of signal flow, indicating the parallel computation of motor commands. Overall, this study reveals the neural dynamics of active vision, which are efficiently linked to the natural rhythms of visual exploration. An ECoG array covering the marmoset’s entire cerebral cortex revealed neural dynamics of the visual system; the dorsal and ventral streams activate one after another following saccade, constituting the rhythm of natural visual behavior.
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