Primary visual cortex: awareness and blindsight.

Primary visual cortex: awareness and blindsight.
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DOI:
10.1146/annurev-neuro-062111-150356
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发表时间:
2012
影响因子:
13.9
通讯作者:
Leopold DA
Leopold DA
中科院分区:
医学1区
文献类型:
--
作者:
Leopold DA

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初级视觉皮层,或V1,是人类和猴子视觉输入的主要端脑受体。它在皮质区中是独一无二的,因为它的破坏会导致慢性失明,这导致人们猜测它可能在产生视觉意识方面发挥特殊或直接的作用。为了探讨这个问题,我们回顾了实验,使用了两个强大的范例,心理物理视觉抑制和慢性V1消融,每一个都破坏了感知显着视觉刺激的能力。我们专注于最近的研究,从非人灵长类动物使用解剖学,神经生理学和行为的范例,以了解V1的感知的作用。我们还审查有关的基础上的无意识的视觉,或盲视,可能发生V1损伤后的调查结果。我们的结论是,V1在灵长类动物的视觉中的关键作用,自然从它的位置作为视觉信号的瓶颈,但很少有证据支持其直接贡献的视觉意识。
The primary visual cortex, or V1, is the principal telencephalic recipient of visual input in humans and monkeys. It is unique among cortical areas in that its destruction results in chronic blindness, leading to speculation that it may have a special or direct role in generating visual awareness. To explore this issue we review experiments that have used two powerful paradigms, psychophysical visual suppression and chronic V1 ablation, each of which disrupts the ability to perceive salient visual stimuli. We focus on recent studies from the nonhuman primate using anatomical, neurophysiological and behavioral paradigms to understand V1's role in perception. We also review findings pertaining to the basis of unconscious vision, or blindsight, that can occur after V1 damage. We conclude that the critical role of V1 in primate vision follows naturally from its position as a bottleneck of visual signals, but that there is little evidence to support its direct contribution to visual awareness.
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