Effects of coffee and tea consumption on urinary incontinence in female twins.

Effects of coffee and tea consumption on urinary incontinence in female twins.
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DOI:
10.1111/j.1471-0528.2011.02930.x
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发表时间:
2011-06
期刊:
BJOG : an international journal of obstetrics and gynaecology
影响因子:
--
通讯作者:
Iliadou AN
Iliadou AN
中科院分区:
其他
文献类型:
--
作者:
Tettamanti G;Altman D;Pedersen NL;Bellocco R;Milsom I;Iliadou AN

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目的:评估饮用咖啡和茶对尿失禁症状的影响。基于人口的研究瑞典双胞胎登记处2005年,瑞典所有在1959-1985年间出生的双胞胎(n=42 852)被邀请参加一项基于网络的调查,以筛查常见的复杂疾病和常见的暴露。目前的研究仅限于女性双胞胎,至少有一种尿路症状和喝咖啡和茶的信息(n=14031)。用95%可信区间(CI)的优势比(OR)来估计喝咖啡、喝茶和尿失禁以及夜尿之间的关系。与不喝咖啡的女性相比,摄入大量咖啡的女性发生尿失禁的风险更低(OR为0.78,95%可信区间为0.64-0.98)。咖啡摄入量与大小便失禁亚型无显著相关性,而大量饮茶与膀胱过度活动(OR1.34,95%可信区间11.07-1.67)和夜尿症(OR 1.18,95%可信区间1.01-1.38)有明确关联。来自同卵双胞胎对照分析的结果表明,Logistic回归分析中观察到的关联主要是由于家庭影响。这项研究表明,喝咖啡和茶对尿失禁症状的影响有限。家族性和遗传性的影响可能混淆了先前研究中观察到的关联。
To assess the effect of coffee and tea consumption on symptoms of urinary incontinence. Population based study The Swedish Twin Register In 2005, all twins born between 1959–1985 in Sweden (n = 42 852) were invited to participate in a web-based survey to screen for common complex diseases and common exposures. The present study was limited to female twins with information about at least one urinary symptoms and coffee and tea consumption (n = 14 031). The association between coffe and tea consumption and urinary incontinence, as well as, nocturia was estimated as odds ratios (ORs) with 95% confidence intervals (CIs). Women with a high coffee intake were at lower risk of any urinary incontinence (OR 0.78, 95% confidence intervals (CI) 0.64-0.98) compared to women not drinking coffee. Coffee intake and incontinence subtypes showed no significant associations whereas high tea consumption was specifically associated with a risk for overactive bladder (OR 1.34, 95% CI 11.07-1.67) and nocturia (OR 1.18, 95% CI 1.01-1.38). Results from co-twin control analysis suggested that the associations observed in logistic regression were mainly due to familial effects. This study suggests that coffee and tea consumption has a limited effect on urinary incontinence symptoms. Familial and genetic effects may have confounded the associations observed in previous studies.
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