Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies.
Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies.
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DOI：
10.1007/s10875-017-0426-2
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发表时间：
2017-10
影响因子：
9.1
通讯作者：
Tang MLK
中科院分区：
文献类型：
--
作者：
Sullivan KE;Bassiri H;Bousfiha AA;Costa-Carvalho BT;Freeman AF;Hagin D;Lau YL;Lionakis MS;Moreira I;Pinto JA;de Moraes-Pinto MI;Rawat A;Reda SM;Reyes SOL;Seppänen M;Tang MLK
在当今的全球经济和负担得起的度假旅行中，越来越重要的是，到另一个国家的游客和他们的医生熟悉新出现的感染、特定地理区域特有的感染以及与旅行过程相关的风险。对于原发性免疫缺陷疾病（PIDD）患者来说，这一点尤为重要。最近一项针对旅行者发热常见原因的综述为一般人群提供了重要信息Thwaites and Day（N Engl J Med 376：548-560，）。这篇综述涵盖了与PIDD患者旅行特别相关的关键感染和管理问题。本综述将讨论不断变化的感染景观的背景下，突出关注的特定感染，并在免疫功能低下的患者中描述不同的感染表型。本次审查的组织将解决环境驱动新出现的感染和几个独特的PIDD患者的关注。第一部分涉及一般考虑，第二部分根据传播机制组织特定感染的概况，第三部分重点关注PIDDs患者的独特表型和独特易感性。本综述不涉及大多数寄生虫病。参考表提供了比正文中描述的更广泛的感染的容易获得的信息。
In today’s global economy and affordable vacation travel, it is increasingly important that visitors to another country and their physician be familiar with emerging infections, infections unique to a specific geographic region, and risks related to the process of travel. This is never more important than for patients with primary immunodeficiency disorders (PIDD). A recent review addressing common causes of fever in travelers provides important information for the general population Thwaites and Day (N Engl J Med 376:548-560,). This review covers critical infectious and management concerns specifically related to travel for patients with PIDD. This review will discuss the context of the changing landscape of infections, highlight specific infections of concern, and profile distinct infection phenotypes in patients who are immune compromised. The organization of this review will address the environment driving emerging infections and several concerns unique to patients with PIDD. The first section addresses general considerations, the second section profiles specific infections organized according to mechanism of transmission, and the third section focuses on unique phenotypes and unique susceptibilities in patients with PIDDs. This review does not address most parasitic diseases. Reference tables provide easily accessible information on a broader range of infections than is described in the text.
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