Gene-environment interactions across development: Exploring DRD2 genotype and prenatal smoking effects on self-regulation.
Gene-environment interactions across development: Exploring DRD2 genotype and prenatal smoking effects on self-regulation.
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DOI：
10.1037/a0014550
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发表时间：
2009-01
影响因子：
4
通讯作者：
Huggenvik, Jodi I.
中科院分区：
文献类型：
--
作者：
Wiebe, Sandra A.;Espy, Kimberly Andrews;Stopp, Christian;Respass, Jennifer;Stewart, Peter;Jameson, Travis R.;Gilbert, David G.;Huggenvik, Jodi I.
Genetic factors dynamically interact with both pre- and postnatal environmental influences to shape development. Considerable attention has been devoted to gene-environment interactions (GxE) on important outcomes. It is also important to consider the possibility that these GxE effects may vary across development, particularly for constructs like self-regulation that emerge slowly, depend on brain regions that change qualitatively in different developmental periods, and thus may be manifested differently. To illustrate one approach to explore such developmental patterns, the relation between variation in the TaqIA polymorphism, related to D2 dopamine receptor expression and availability, and prenatal exposure to tobacco, was examined in two exploratory studies. First, in 4-week-old neonates, genotype-exposure interactions were observed for attention and irritable reactivity, but not for stress dysregulation. Second, in preschool children, genotype was related to Trails-P task performance on conditions requiring executive control, and children with both the A1+ genotype and a history of prenatal tobacco exposure displayed disproportionately poor performance. Despite study limitations, these results illustrate the importance of examining the interplay between genetic and prenatal environmental factors across development.
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影响因子：
4.3
作者：
Berman, S;Ozkaragoz, T;Noble, EP
通讯作者：
Noble, EP
影响因子：
2.2
作者：
Bakermans-Kranenburg, Marian J.;van Ijzendoorn, Marinus H.
通讯作者：
van Ijzendoorn, Marinus H.
影响因子：
17.7
作者：
Diamond, A;Briand, L;Gehlbach, L
通讯作者：
Gehlbach, L
影响因子：
25
作者：
Bishop, S;Duncan, J;Lawrence, AD
通讯作者：
Lawrence, AD
DOI：
10.1111/j.1471-0528.1993.tb14262.x
发表时间：
1993-08-01
期刊：
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
影响因子：
--
作者：
BARDY, AH;SEPPALA, T;HIILESMAA, VK
通讯作者：
HIILESMAA, VK