Maturation of the human fetal startle response: evidence for sex-specific maturation of the human fetus.
Maturation of the human fetal startle response: evidence for sex-specific maturation of the human fetus.
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DOI：
10.1016/j.earlhumdev.2009.08.001
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发表时间：
2009-10
影响因子：
2.5
通讯作者：
Sandman, Curt A.
中科院分区：
文献类型：
--
作者：
Buss, Claudia;Davis, Elysia Poggi;Class, Quetzal A.;Gierczak, Matt;Pattillo, Carol;Glynn, Laura M.;Sandman, Curt A.
尽管有证据表明，早期胎儿的经验施加编程影响以后的神经发育和健康风险，很少有人类胎儿行为的前瞻性研究报告。在一项前瞻性纵向研究中，通过监测191对母体/胎儿的胎心率（FHR）对振动声刺激（VAS）的反应，连续评估胎儿神经系统的成熟。在26周胎龄（GA）时未检测到反应。在31周GA时观察到FHR对VAS反应的性别特异性、年龄特征性变化。雄性表现出较大的反应，并继续表现出成熟的变化，直到37周的GA，但女性，提出了一个成熟的胎心率惊吓反应的31周的GA。结果表明，有不同的成熟率在男性和女性胎儿，可能有影响性别特异性编程的影响。
Despite the evidence for early fetal experience exerting programming influences on later neurological development and health risk, very few prospective studies of human fetal behavior have been reported. In a prospective longitudinal study, fetal nervous system maturation was serially assessed by monitoring fetal heart rate (FHR) responses to vibroacoustic stimulation (VAS) in 191 maternal/fetal dyads. Responses were not detected at 26 weeks gestational age (GA). Sex-specific, age-characteristic changes in the FHR response to VAS were observed by 31 weeks’ GA. Males showed larger responses and continued to exhibit maturational changes until 37 weeks’ GA, females however, presented with a mature FHR startle response by 31 weeks’ GA. The results indicate that there are different rates of maturation in the male and female fetus that may have implications for sex-specific programming influences.
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影响因子：
2.2
作者：
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通讯作者：
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影响因子：
2.5
作者：
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DOI：
10.1016/s0002-9378(88)80148-0
发表时间：
1988-10-01
影响因子：
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作者：
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通讯作者：
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