Effect of acupuncture versus usual care on sleep quality in cancer survivors with chronic pain: Secondary analysis of a randomized clinical trial.
Effect of acupuncture versus usual care on sleep quality in cancer survivors with chronic pain: Secondary analysis of a randomized clinical trial.
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DOI：
10.1002/cncr.34766
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发表时间：
2023-07-01
期刊：
影响因子：
6.2
通讯作者：
Mao, Jun J.
中科院分区：
文献类型：
--
作者：
Yang, Mingxiao;Baser, Raymond E.;Liou, Kevin T.;Li, Susan Q.;Piulson, Lauren;Panageas, Katherine S.;Mao, Jun J.
慢性疼痛对睡眠有负面影响；目前尚不清楚针灸缓解疼痛是否有助于改善癌症幸存者的睡眠质量。本研究旨在评估针灸与常规护理对患有睡眠障碍和慢性肌肉骨骼疼痛的癌症幸存者的睡眠质量的影响。我们分析了和平随机临床试验的睡眠结果数据。我们对临床上有明显睡眠障碍和慢性肌肉骨骼疼痛的癌症幸存者进行了10周的治疗，比较了电针或耳针与常规护理改善睡眠质量的效果。我们用匹兹堡睡眠质量指数(PSQI)的全球评分来衡量睡眠质量。在268名参与者中(平均[标准差]年龄，61.412.6岁；女性[71.3%]；平均[标准差]基线PSQI全球评分，10.3[3.3]分)，与常规护理相比，电针导致PSQI全球评分从基线到10周下降1.42点(95%可信区间0.452.38；P=0.004)和耳针1.59点(95%可信区间0.622.55；P=0.001)。从随机开始，针刺组睡眠质量的改善持续了24周。此外，与常规护理组相比，电针组和耳针组有更大比例的患者在临床上有意义的睡眠质量改善(41.0%和42.9%对21.4%，P=0.044)。在患有睡眠障碍和慢性疼痛的癌症幸存者中，电针和耳针在临床上能够持续改善睡眠质量。这些发现表明，针灸可能是一种循证的非药物干预措施，以改善患有疼痛的癌症幸存者的睡眠健康。这项研究分析了一项发表的随机临床试验的睡眠质量数据，该试验评估了电针或耳针与常规护理对癌症幸存者缓解疼痛的效果。这项分析包括268名在基线时患有睡眠障碍和慢性肌肉骨骼疼痛的预先指定的参与者，并发现与接受常规护理的患者相比，使用针灸缓解疼痛的患者在睡眠质量方面表现出更大的改善。治疗结束后持续通过针灸改善睡眠质量。在患有睡眠障碍和慢性疼痛的癌症幸存者中，与常规护理相比，电针和耳针都改善了睡眠质量。针灸治疗对睡眠质量的改善作用在随机分组后持续到24周。
Chronic pain negatively impacts sleep; it is unclear whether pain relief from acupuncture contributes to sleep quality improvements in cancer survivors. This study aimed to evaluate the effect of acupuncture versus usual care on sleep quality among cancer survivors with comorbid sleep disturbance and chronic musculoskeletal pain. We analyzed sleep outcome data from the PEACE randomized clinical trial. We compared electroacupuncture or auricular acupuncture versus usual care for sleep quality improvement over ten weeks of treatment among cancer survivors with clinically significant sleep disturbance and chronic musculoskeletal pain at baseline. We measured sleep quality with the Pittsburgh Sleep Quality Index (PSQI) global score. Among 268 participants (mean [standard deviation (SD)] age, 61.4 [12.6] years; 191 women [71.3%]; mean [SD] baseline PSQI global score, 10.3 [3.3] points), electroacupuncture resulted in greater reductions in the PSQI global score from baseline to ten weeks by 1.42 points (95% Confidence Interval [CI], 0.45–2.38; P=0.004) and auricular acupuncture by 1.59 points (95% CI, 0.62–2.55; P=0.001) compared to usual care. Improvement in sleep quality for the acupuncture groups was sustained for 24 weeks from randomization. Further, a greater proportion of patients in the electroacupuncture and auricular acupuncture groups had clinically meaningful improvement in sleep quality compared to the usual care group (41.0% and 42,9% vs. 21.4%, P=0.044). Among cancer survivors with comorbid sleep disturbance and chronic pain, electroacupuncture and auricular acupuncture produced clinically relevant and persistent improvement in sleep quality. These findings suggest acupuncture may be an evidence-based nonpharmacologic intervention to improve sleep health for cancer survivors with pain. This study analyzed the sleep quality data from a published randomized clinical trial that evaluated the effect of electroacupuncture or auricular acupuncture versus usual care on pain relief among people who survived cancer. This analysis included a prespecified subgroup of 268 participants with co-occurring sleep disturbance and chronic musculoskeletal pain at baseline and found that patients using acupuncture for pain relief demonstrated greater improvements in sleep quality compared with patients receiving usual care. Sleep quality improvement by acupuncture was sustained after the treatment ended. Among cancer survivors with comorbid sleep disturbance and chronic pain, both electroacupuncture and auricular acupuncture improved sleep quality compared to usual care. The improvement in sleep quality by acupuncture treatment was sustained to 24 weeks after randomization.
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影响因子：
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