The Potential of Exosomal RNAs in Atherosclerosis Diagnosis and Therapy.

The Potential of Exosomal RNAs in Atherosclerosis Diagnosis and Therapy.
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DOI:
10.3389/fneur.2020.572226
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发表时间:
2020
影响因子:
3.4
通讯作者:
Ma A
Ma A
中科院分区:
医学3区
文献类型:
--
作者:
Yang W;Pan X;Ma A

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Atherosclerosis is an inflammatory disease that can lead to cardiovascular disorders and stroke. In the atherosclerosis microenvironment, exosomes secreted from various cells, especially macrophage-derived exosomes, play an important role in cell–cell communication and cellular biological functions. In this article, we review previous studies on exosomal RNAs and discuss their potential value in atherosclerosis diagnosis and therapy. Based on our research, we concluded that macrophage exosomes have potential value in atherosclerosis diagnosis and therapy. However, there is a need for future studies to further investigate methods of exosome isolation and targeting.
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