Test-retest reliability of task-based and resting-state blood oxygen level dependence and cerebral blood flow measures.
Test-retest reliability of task-based and resting-state blood oxygen level dependence and cerebral blood flow measures.
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DOI：
10.1371/journal.pone.0206583
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Dukart J
中科院分区：
文献类型：
--
作者：
Holiga Š;Sambataro F;Luzy C;Greig G;Sarkar N;Renken RJ;Marsman JC;Schobel SA;Bertolino A;Dukart J
尽管他们的广泛使用，只有有限的信息是可用的比较重测信度的任务为基础的功能和静息状态磁共振成像措施的血氧水平依赖性（tb-fMRI和rs-fMRI）和脑血流量（CBF）使用动脉自旋标记。这些信息对于设计适当的纵向研究至关重要。在这里，我们全面量化和比较的重测信度和再现性性能的8个常用的功能磁共振成像任务，6 rs-fMRI指标和CBF在30名健康志愿者。我们发现，在不同的tb-fMRI范式和rs-fMRI指标，从差到优的重测信度性能的变化很大。在结核-功能磁共振成像激活的更大程度上是链接到更高的受试者之间的各自的任务的可靠性，这表明激活量的差异可以被用作第一可靠性估计的新结核-功能磁共振成像范例。对于rs-fMRI，局部活动估计的良好可靠性被全局连接度量的不良性能所掩盖。评价的CBF措施提供了一个良好的一般优秀的测试可靠性匹配或超越最好的执行tb-fMRI和rs-fMRI指标。这一全面的努力允许直接比较的重测信度之间的评价MRI域和措施，以帮助设计未来的tb-fMRI，rs-fMRI和CBF研究。
Despite their wide-spread use, only limited information is available on the comparative test-retest reliability of task-based functional and resting state magnetic resonance imaging measures of blood oxygen level dependence (tb-fMRI and rs-fMRI) and cerebral blood flow (CBF) using arterial spin labeling. This information is critical to designing properly powered longitudinal studies. Here we comprehensively quantified and compared the test-retest reliability and reproducibility performance of 8 commonly applied fMRI tasks, 6 rs-fMRI metrics and CBF in 30 healthy volunteers. We find large variability in test-retest reliability performance across the different tb-fMRI paradigms and rs-fMRI metrics, ranging from poor to excellent. A larger extent of activation in tb-fMRI is linked to higher between-subject reliability of the respective task suggesting that differences in the amount of activation may be used as a first reliability estimate of novel tb-fMRI paradigms. For rs-fMRI, a good reliability of local activity estimates is paralleled by poor performance of global connectivity metrics. Evaluated CBF measures provide in general a good to excellent test-reliability matching or surpassing the best performing tb-fMRI and rs-fMRI metrics. This comprehensive effort allows for direct comparisons of test-retest reliability between the evaluated MRI domains and measures to aid the design of future tb-fMRI, rs-fMRI and CBF studies.
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