Recombination and the nature of bacterial speciation.

Recombination and the nature of bacterial speciation.
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DOI:
10.1126/science.1127573
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发表时间:
2007-01-26
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Spratt BG
Spratt BG
中科院分区:
其他
文献类型:
--
作者:
Fraser C;Hanage WP;Spratt BG

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基因调查揭示了细菌的多样性,并导致用于分类的物种概念受到质疑。定义细菌物种的一个困难来自于高重组率,这导致DNA在相对较远的亲缘关系的细菌之间转移。这一过程可以用来自然地定义物种,但障碍并不明显。在这里,我们回顾了细菌物种形成的概念模型,并模拟了硅胶中的物种形成。我们的发现表明,重组率及其与遗传分化的关系对结果有很大的影响:我们建议区分克隆分化和有性物种形成。因此,为了理解细菌多样性,我们不仅需要来自遗传调查的数据,还需要来自选择压力和重组率的实验确定的数据,以及来自理论模型的数据。
Genetic surveys are uncovering the diversity of bacteria, and are causing the species concepts used to categorize these to be questioned. One difficulty in defining bacterial species arises from the high rates of recombination that results in the transfer of DNA between relatively distantly related bacteria. Barriers to this process, which could be used to define species naturally, are not apparent. Here, we have reviewed conceptual models of bacterial speciation and simulate speciation in silico. Our findings suggest that the rate of recombination and its relation to genetic divergence, have a strong influence on outcomes: we propose that a distinction be made between clonal divergence and sexual speciation. Hence, to make sense of bacterial diversity we need data not only from genetic surveys, but also from experimental determination of selection pressures and recombination rates, and from theoretical models.
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影响因子: 56.9
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