A pilot randomized control trial of online exposure for eating disorders and mechanisms of change delivered after discharge from intensive eating disorder care: A registered report.

A pilot randomized control trial of online exposure for eating disorders and mechanisms of change delivered after discharge from intensive eating disorder care: A registered report.
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DOI:
10.1002/eat.23603
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发表时间:
2021-11
影响因子:
5.5
通讯作者:
Eley, Thalia C.
Eley, Thalia C.
中科院分区:
医学2区
文献类型:
--
作者:
Levinson, Cheri A.;Ralph-Nearman, Christina;Brown, Mackenzie L.;Gardner, Taylor;Cardi, Valentina;Treasure, Janet;Purves, Kirstin;Eley, Thalia C.

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超过50%的进食障碍(ED)患者将在治疗出院后6个月内重新接受治疗,通常是由于持续的认知性ED病理。针对强化治疗出院后未缓解的认知性ED病理的干预措施对于防止再入院至关重要。想象暴露疗法有助于接近日常生活中无法获得的令人恐惧的刺激(例如,体重迅速增加)。在目前的试点随机对照试验(RCT)中,参与者将在强化治疗出院后一个月内被随机分配到五个疗程的在线想象暴露条件(n=65)或对照在线写作和思维干预(n=65)。暴露参与者写下并想象自己患有勃起功能障碍的恐惧,而控制组参与者一般会写下他们的勃起功能障碍。我们将检查治疗条件的可行性和可接受性,以及想象暴露是否比对照条件更有效地防止再入院。我们将测试想象暴露治疗在减少ED症状以及对食物和体重增加的恐惧方面的有效性,以及恐惧学习是否是与ED病理相关的变化机制。最终,这项研究将导致开发一种基于恐惧条件反射靶点的易于部署的重新入院预防治疗。
More than 50% of individuals with an eating disorder (ED) will readmit to treatment within 6 months of treatment discharge and often due to persistent cognitive ED pathology. Interventions addressing unremitted cognitive ED pathology following discharge from intensive treatment are crucial to prevent readmission. Imaginal exposure therapy facilitates the approach of feared stimuli not accessible in everyday life (e.g., rapidly gaining weight). In the current pilot randomized control trial (RCT), participants will be randomly assigned to a five-session online imaginal exposure condition (n = 65) or a control online writing and thinking intervention (n = 65) within a month of discharge from intensive treatment. Exposure participants write about and imagine an ED fear and control participants will write about their ED generally. We will examine the feasibility and acceptability of the treatment conditions and whether imaginal exposure is more effective in preventing readmission than the control condition. We will test the efficacy of the imaginal exposure treatment in reducing ED symptoms and fears of food and weight gain, and whether fear learning is a mechanism of change related to ED pathology. Ultimately, this research will lead to the development of an easily deployable readmission prevention treatment based on fear conditioning targets.
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影响因子: --
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