Coronavirus Disease 2019 (COVID-19) in Italy: Double Reading of Chest CT Examination.
Coronavirus Disease 2019 (COVID-19) in Italy: Double Reading of Chest CT Examination.
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意大利 2019 年冠状病毒病 (COVID-19)：胸部 CT 检查的双重解读。
DOI：
10.3390/biology10020089
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发表时间：
2021-01-25
期刊：
影响因子：
4.2
通讯作者：
Cappabianca S
中科院分区：
文献类型：
--
作者：
Reginelli A;Grassi R;Feragalli B;Belfiore MP;Montanelli A;Patelli G;La Porta M;Urraro F;Fusco R;Granata V;Petrillo A;Giacobbe G;Russo GM;Sacco P;Grassi R;Cappabianca S
该手稿的目的是评估专家放射科医生对COVID-19病毒性肺炎逆转录实时荧光聚合酶链反应（RT-PCR）检测与CT报告不一致的患者进行胸部计算机断层扫描（CT）检查的第二次阅读的性能。CT的双重阅读可以增加大流行地区COVID-19患者放射学解释的诊断信心。使用第二读片员和结构化报告进行COVID-19诊断可以降低COVID-19病毒性肺炎RT-PCR结果与CT诊断之间的不一致病例率。对COVID-19病毒性肺炎逆转录实时荧光聚合酶链反应（RT-PCR）检测结果与CT报告不一致的患者，评估放射科专家对胸部计算机断层扫描（CT）检查进行二次阅读的性能。这项回顾性研究纳入了378名患者（121名女性和257名男性;中位年龄为71岁，范围为29-93岁），并对可疑的COVID-19感染进行了RT-PCR检测。所有患者均接受CT检查，以评估COVID-19对肺部疾病的影响。CT图像首先由两名放射科医生进行审查，他们确定了COVID-19的典型CT模式，然后由另外两名放射科医生使用CT结构化报告重新分析COVID-19诊断。加权k值用于评价阅片者间一致性。RT-PCR执行和CT扫描之间的中位时间窗为0天，范围为（-9，11）天。RT-PCR检测阳性328例（86.8%）。60例病毒性肺炎的RT-PCR与CT表现不一致。第二次阅读改变了16/60例（26.7%）的CT诊断，有助于提高与RT-PCR的一致性。其中RT-PCR阳性假阴性8例，RT-PCR阴性假阳性36例。CT诊断肺癌的敏感性、特异性、阳性预测值和阴性预测值分别为97.3%、53.8%、89.0%和88.4%。CT扫描的双重阅读和专家第二阅读者可以增加COVID-19患者放射学解释的诊断信心。
The objective of the manuscript was to assess the performance of the second reading of chest compute tomography (CT) examinations by expert radiologists in patients with discordance between the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID-19 viral pneumonia and the CT report. Double reading of CT could increase the diagnostic confidence of radiological interpretation in COVID-19 patients in a pandemic area. Using second readers and a structured report for COVID-19 diagnosis could reduce the rate of discrepant cases between RT-PCR result and CT diagnosis for COVID-19 viral pneumonia. To assess the performance of the second reading of chest compute tomography (CT) examinations by expert radiologists in patients with discordance between the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID-19 viral pneumonia and the CT report. Three hundred and seventy-eight patients were included in this retrospective study (121 women and 257 men; 71 years median age, with a range of 29–93 years) and subjected to RT-PCR tests for suspicious COVID-19 infection. All patients were subjected to CT examination in order to evaluate the pulmonary disease involvement by COVID-19. CT images were reviewed first by two radiologists who identified COVID-19 typical CT patterns and then reanalyzed by another two radiologists using a CT structured report for COVID-19 diagnosis. Weighted k values were used to evaluate the inter-reader agreement. The median temporal window between RT-PCRs execution and CT scan was zero days with a range of (−9, 11) days. The RT-PCR test was positive in 328/378 (86.8%). Discordance between RT-PCR and CT findings for viral pneumonia was revealed in 60 cases. The second reading changed the CT diagnosis in 16/60 (26.7%) cases contributing to an increase the concordance with the RT-PCR. Among these 60 cases, eight were false negative with positive RT-PCR, and 36 were false positive with negative RT-PCR. Sensitivity, specificity, positive predictive value and negative predictive value of CT were respectively of 97.3%, 53.8%, 89.0%, and 88.4%. Double reading of CT scans and expert second readers could increase the diagnostic confidence of radiological interpretation in COVID-19 patients.
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影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
DOI：
10.1186/s13054-018-2105-y
发表时间：
2018-08-18
期刊：
Critical care (London, England)
影响因子：
--
作者：
See KC;Ong V;Tan YL;Sahagun J;Taculod J
通讯作者：
Taculod J
影响因子：
3.7
作者：
Arevalo-Rodriguez I;Buitrago-Garcia D;Simancas-Racines D;Zambrano-Achig P;Del Campo R;Ciapponi A;Sued O;Martinez-García L;Rutjes AW;Low N;Bossuyt PM;Perez-Molina JA;Zamora J
通讯作者：
Zamora J
可以定量用于SARS-COV-2的RT-PCR有助于更好地治疗患者并控制冠状病毒病2019年大流行。
影响因子：
1.6
作者：
Rattan A;Ahmad H
通讯作者：
Ahmad H
中国武汉市 138 例 2019 新型冠状病毒感染肺炎住院患者的临床特征。
影响因子：
120.7
作者：
Wang, Dawei;Hu, Bo;Peng, Zhiyong
通讯作者：
Peng, Zhiyong