Malignant tumor cell lines produce interleukin-1-like factor

Malignant tumor cell lines produce interleukin-1-like factor
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恶性肿瘤细胞系产生白细胞介素1样因子

DOI:
10.1007/bf02623644
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发表时间:
1988
期刊:
In Vitro Cellular & Developmental Biology
影响因子:
--
通讯作者:
K. Takada
K. Takada
中科院分区:
--
文献类型:
--
作者:
Shinobu Miyauchi;T. Moroyama;S. Kyoizumi;J. Asakawa;T. Okamoto;K. Takada

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用胸腺细胞和成纤维细胞增殖试验检测了64个恶性肿瘤细胞系的条件培养基中白细胞介素-1(IL-1)的活性。16个细胞系显示高IL-1活性。这些活动与人IL-1的比较表明,一些生物学特性之间的相似性。但细胞来源与IL-1活性无相关性。这些结果表明,大多数恶性细胞可能产生IL-1样因子的可能性。
SummarySixty-four malignant cell lines were examined for interleukin-1 (IL-1) activities in their conditioned medium using thymocyte and fibroblast proliferation assays. Sixteen cell lines showed high IL-1 activity. Comparison of these activities with human IL-1 showed similarity between some biological properties. However there was no correlation between cell origin and IL-1 activity. These results suggest the possibility that most malignant cells may produce an IL-1-like factor.
肝素结合内皮细胞生长因子的纯化和表征。
DOI: --
发表时间: 1986
期刊: The Journal of biological chemistry
影响因子: --
作者:
Lobb,R;Sasse,J;Sullivan,R;Shing,Y;D'Amore,P;Jacobs,J;Klagsbrun,M
通讯作者: Klagsbrun,M
DOI: 10.1073/pnas.81.24.7907
发表时间: 1984-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
AURON, PE;WEBB, AC;DINARELLO, CA
通讯作者: DINARELLO, CA