Hormones and nocturnal penile tumescence in healthy aging men
Hormones and nocturnal penile tumescence in healthy aging men
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健康老年男性的激素和夜间阴茎肿胀
DOI：
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发表时间：
1993
影响因子：
3.8
通讯作者：
P. Schreiner
中科院分区：
文献类型：
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作者：
R. Schiavi;D. White;J. Mandeli;P. Schreiner
目前还没有关于健康老年男性内源性垂体和性腺激素与夜间阴茎肿胀 (NPT) 之间关系的信息。 67 名年龄在 45 至 74 岁之间的已婚志愿者在睡眠实验室进行了 4 个晚上的研究，最后一个晚上每 20 分钟连续进行一次血液采样。生物可利用睾酮 (bT) 与多项 NPT 测量值显着相关，而总睾酮、雌二醇、LH 和催乳素大多与 NPT 无关。在通过多元回归调整年龄对总受试者样本中 bT 和 NPT 变量的影响后，所有 bT-NPT 相关性都失去了显着性。按年龄组进行的 bT-NPT 关系分析显示，55 至 64 岁男性的 bT 与 NPT 持续时间之间存在显着相关性，但在较年轻和较年长的年龄组中没有统计学关系。随着年龄的增长，NPT 激活的中心阈值发生变化，这或许可以解释 bT 在睡眠勃起中的年龄依赖性效应。
There is no information on the relationship between endogenous pituitary and gonadal hormones and nocturnal penile tumescence (NPT) in healthy aging men. Sixty-seven married volunteers ages 45–74 years were studied in the sleep laboratory for 4 nights with the last night devoted to sequential blood sampling every 20 min. Bioavailable testosterone (bT) correlated significantly with several NPT measures while total testosterone, estradiol, LH, and prolactin were mostly unrelated to NPT. All bT—NPT correlations lost their significance after adjustment by multiple regression for the effect of age on both bT and NPT variables in the total subject sample. Analysis of bT—NPT relations by age groups revealed a significant association between bT and duration NPT in men ages 55 to 64 years, but no statistical relations in younger and older age groups. Changes in the central threshold of activation of NPT as age progresses may explain the age-dependent effect of bT in sleep erections.
影响因子：
5.8
作者：
KWAN, M;GREENLEAF, WJ;DAVIDSON, JM
通讯作者：
DAVIDSON, JM
夜间阴茎肿胀评估勃起障碍：批判性评论。
影响因子：
2.5
作者：
Schiavi,RC
通讯作者：
Schiavi,RC