Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction.
Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction.
复制标题
急性心肌梗死后患者焦虑与压力反射心脏控制减弱的关系。
DOI：
10.1067/mhj.2002.120404
复制
发表时间：
2002
影响因子：
4.8
通讯作者：
Carney,RobertM
中科院分区：
文献类型：
--
作者：
Watkins,LanaL;Blumenthal,JamesA;Carney,RobertM
背景尽管抑郁症与急性心肌梗死（AMI）后患者死亡率的增加有关，但抑郁症对自主神经系统控制心率的影响却知之甚少。本研究旨在评估急性心肌梗死患者的压力反射敏感性（BRS）受损是否与抑郁有关。方法对204例AMI住院患者在AMI后6 ± 3（平均值±标准差）d进行评估。使用交叉频谱分析评估BRS，以测量压力感受器介导的R-R间期振荡。抑郁症的确定使用诊断访谈时间表，抑郁症状的严重程度与贝克抑郁量表。为了调整焦虑的可能差异，我们还使用Spielberger状态焦虑量表测量了状态焦虑。结果抑郁与BRS无显著相关。然而，在多变量分析中，在控制了年龄、血压和呼吸频率等潜在混杂变量后，焦虑与低BRS显著相关。高焦虑组和低焦虑组的比较（基于状态焦虑评分的中位数）显示，在调整年龄、血压和呼吸频率的差异后，焦虑评分较高的患者BRS降低约20%（4.7 ± 3.2 ms/mm Hg vs 5.7 ± 3.3 ms/mm Hg，P <0.05）。结论AMI后高水平的焦虑与迷走神经控制能力下降有关，而抑郁与此无关。(Am心脏J 2002;143：460-6。）
Background Although depression has been associated with increased mortality in patients after acute myocardial infarction (AMI), little is known about the effects of depression on autonomic nervous system control of heart rate. This study evaluated whether depression is associated with impaired baroreflex sensitivity (BRS) in patients with AMI. Methods Two hundred four hospitalized patients with AMI were evaluated 6 ± 3 (mean ± SD) days after AMI. BRS was assessed using cross-spectral analysis to measure baroreceptor-mediated R-R interval oscillations. Depression was determined using the Diagnostic Interview Schedule, and severity of depressive symptoms was measured with the Beck Depression Inventory. In order to adjust for possible differences in anxiety, we also measured state anxiety using the Spielberger State Anxiety Inventory. Results Depression was not significantly related to BRS. However, anxiety was significantly related to low BRS in multivariate analysis, after the potentially confounding variables of age, blood pressure, and respiratory frequency were controlled for. Comparison of groups with high and low anxiety (on the basis of a median split of state anxiety scores) showed that BRS was reduced by approximately 20% in the patients with the higher anxiety scores (4.7 ± 3.2 ms/mm Hg vs 5.7 ± 3.3 ms/mm Hg, P < .05), after adjustment for differences in age, blood pressure, and respiratory frequency. Conclusions High levels of anxiety, but not depression, are associated with reduced vagal control in patients after AMI. (Am Heart J 2002;143:460-6.)
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DOI：
10.3758/bf03211198
发表时间：
1973-01-01
期刊：
PERCEPTION & PSYCHOPHYSICS
影响因子：
--
作者：
POMERANTZ, JR;GARNER, WR
通讯作者：
GARNER, WR
音调的等音量判断。
影响因子：
1.3
作者：
G. J. Thomas
通讯作者：
G. J. Thomas
音调的属性。
DOI：
--
发表时间：
1934
影响因子：
11.1
作者：
S. S. Stevens
通讯作者：
S. S. Stevens
整体与分析过程模型：答复。
DOI：
--
发表时间：
1979
期刊：
Journal of Experimental Psychology: Human Perception and Performance
影响因子：
--
作者：
G. Lockhead
通讯作者：
G. Lockhead
处理维度刺激：注释。
DOI：
--
发表时间：
1972
期刊：
Psychology Review
影响因子：
--
作者：
G. Lockhead
通讯作者：
G. Lockhead