In vitro antibacterial effect of chlorhexidine added to glass-ionomer cements.
In vitro antibacterial effect of chlorhexidine added to glass-ionomer cements.
复制标题
添加到玻璃离子水门汀中的氯己定的体外抗菌作用。
DOI：
10.1111/j.1600-0722.1991.tb01066.x
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Dan Ericson
中科院分区：
文献类型：
--
作者：
Juliana Ribeiro;Dan Ericson
本研究的目的是调查的抗菌性能的玻璃离子水门汀含有不同浓度的洗必泰和洗必泰可能从化合物的释放。将葡萄糖酸氯己定或二乙酸氯己定与玻璃离子水门汀混合，并在体外进行抗干酪乳杆菌和变形链球菌菌株的试验。采用分光光度法检测混合液中洗必泰的释放。在肉汤培养试验中，混合物中氯己定的浓度越高，对变形链球菌的抗菌作用时间越长，材料变质的趋势越大。琼脂扩散试验表明，细菌抑制的剂量-反应方式。测试的细菌菌株被类似地抑制，并且抗菌特性随时间而降低。少量添加的氯己定从骨水泥中释放。骨水泥的劣化表明该材料可用作清漆样氯己定载体。
The aims of the present study were to investigate the antibacterial properties of glass-ionomer cements containing different concentrations of chlorhexidine and the possible release of chlorhexidine from the compound. Chlorhexidine gluconate or diacetate was mixed with glass-ionomer cements and tested in vitro against strains of Lactobacillus casei and mutans streptococci. A spectrophotometric test was used to monitor the release of chlorhexidine from the mixture. In a broth culture test, the higher the concentrations of chlorhexidine in the mixture, the longer the time of antibacterial effect on Streptococcus mutans and the greater the tendency of the material to deteriorate. Agar diffusion tests revealed bacterial inhibition in a dose-response manner. The tested bacterial strains were similarly inhibited and the antibacterial properties decreased with time. A minor portion of added chlorhexidine was released from the cement. The deterioration of the cements indicates that the material could be useful as a varnish-like chlorhexidine carrier.
影响因子：
2.9
作者：
JEDRYCHOWSKI, JR;CAPUTO, AA;KERPER, S
通讯作者：
KERPER, S