Family health history reporting is sensitive to small changes in wording.
Family health history reporting is sensitive to small changes in wording.
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DOI：
10.1038/gim.2016.45
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发表时间：
2016-12
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影响因子：
--
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家庭健康史通常是通过单项询问收集的，询问患者其家庭成员是否受到某些疾病的影响。这些询问的具体措辞可能会影响个人报告的内容。波士顿儿童医院患者的父母被邀请参加一项基于网络的调查，该调查是关于他们孩子的个人基因组研究结果的回报。参与者报告了11种医疗状况是否影响了他们或他们的家人。随机化决定了参与者是否被特别指示考虑他们的大家庭。2，901名参与者报告了家族健康史。那些被要求考虑他们的大家庭的人更有可能报告11种疾病中的8种的阳性家族史。观察到最大的差异是癌症（65.1% vs 45.7%，p<0.001）、心血管疾病（72.5% vs 56.0%，p<0.001）和内分泌/激素疾病（50.9% vs 36.7%，p<0.001）。对家族健康史查询的措辞方式进行微小的改变可以大大改变患者的反应。临床医生和研究人员需要对患者在健康史报告中忽略大家庭的倾向保持敏感，除非特别要求考虑他们。
Family health history is often collected through single-item queries that ask patients whether or not their family members are affected by certain conditions. The specific wording of these queries may affect what individuals report. Parents of Boston Children’s Hospital patients were invited to participate in a web-based survey about the return of individual genomic research results about their children. Participants reported whether 11 types of medical conditions affected them or their family. Randomization determined whether or not participants were specifically instructed to consider their extended family. 2,901 participants reported family health history. Those asked to consider their extended family were more likely to report a positive family history for 8 of 11 medical conditions. The largest differences were observed for cancer (65.1% vs 45.7%, p<0.001), cardiovascular conditions (72.5% vs 56.0%, p<0.001), and endocrine/hormonal conditions (50.9% vs 36.7%, p<0.001). Small alterations to the way family health history queries are worded can substantially change patient responses. Clinicians and researchers need to be sensitive about patients’ tendencies to omit extended family from health history reporting unless specifically asked to consider them.
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影响因子：
2.2
作者：
Wood, Marie E.;Stockdale, Alan;Flynn, Brian S.
通讯作者：
Flynn, Brian S.
影响因子：
39.2
作者：
Berg, Alfred O.;Baird, Macaran A.;Williams, Janet K.
通讯作者：
Williams, Janet K.
DOI：
10.1177/1556264615599620
发表时间：
2015-10-01
影响因子：
1.3
作者：
Holm, Ingrid A.;Iles, Brittany R.;Huntington, Noelle L.
通讯作者：
Huntington, Noelle L.
影响因子：
4.1
作者：
Emslie, C;Hunt, K;Watt, G
通讯作者：
Watt, G
影响因子：
4.4
作者：
COLEMAN, JS
通讯作者：
COLEMAN, JS