Predicting Self-Medication with Cannabis in Young Adults with Hazardous Cannabis Use.
Predicting Self-Medication with Cannabis in Young Adults with Hazardous Cannabis Use.
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DOI：
10.3390/ijerph19031850
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发表时间：
2022-02-07
影响因子：
--
通讯作者：
Mason MJ
中科院分区：
文献类型：
--
作者：
Wallis D;Coatsworth JD;Mennis J;Riggs NR;Zaharakis N;Russell MA;Brown AR;Rayburn S;Radford A;Hale C;Mason MJ
使用大麻来减轻心理和身体痛苦（称为自我药疗）是大麻使用障碍的一个重要危险因素。为了更好地了解这种高风险行为，我们于 2020 年 1 月和 2 月从美国两所大学招募了 290 名年轻人（18-25 岁；45.6% 女性）作为样本，完成一项有关大麻使用和自我药疗的调查。结果：76% 的人支持使用大麻来减少焦虑、睡眠、抑郁、疼痛、孤独、社交不适和注意力集中等问题。在预测自我药疗大麻的原因时，逻辑回归模型显示，较低的 CUDIT-R 分数、经历戒断、生活在大麻非法的州以及女性都与较高的自我药疗率相关。通过测试戒断症状来预测大麻的自我药疗，只有失眠和食欲不振是重要的预测因素。为了进一步探讨年轻人自我药疗的原因，每个原始预测因子都根据自我药疗的七个具体原因进行了回归。经历戒断症状的年轻人更有可能自行治疗疼痛。居住在大麻合法地区的参与者自我治疗焦虑和抑郁的可能性较小。生活在大麻非法的地方也显着预测了因社交不适而进行的自我治疗——尽管预测社交不适的整体模型在统计上并不显着。最后，女性参与者更有可能自我治疗焦虑。这些结果表明，可能患有 CUD 的年轻人普遍存在自我药疗，并强调了他们使用大麻的复杂性。这些发现对于理解年轻人使用大麻与心理和身体困扰相关的原因以及准确治疗患有大麻使用障碍的年轻人具有重要意义。
Using cannabis to reduce psychological and physical distress, referred to as self-medication, is a significant risk factor for cannabis use disorder. To better understand this high-risk behavior, a sample of 290 young adults (ages 18–25; 45.6% female) were recruited from two U.S. universities in January and February of 2020 to complete a survey about their cannabis use and self-medication. Results: seventy-six percent endorsed using cannabis to reduce problems such as anxiety, sleep, depression, pain, loneliness, social discomfort, and concentration. When predicting reasons for self-medication with cannabis, logistic regression models showed that lower CUDIT-R scores, experiencing withdrawal, living in a state where cannabis was illegal, and being female were all associated with higher rates of self-medication. Withdrawal symptoms were tested to predict self-medication with cannabis, and only insomnia and loss of appetite were significant predictors. To further explore why young adults self-medicate, each of the original predictors were regressed on seven specified reasons for self-medication. Young adults experiencing withdrawal were more likely to self-medicate for pain. Participants living where cannabis is legal were less likely to self-medicate for anxiety and depression. Living where cannabis is illegal also significantly predicted self-medicating for social discomfort—though the overall model predicting social discomfort was statistically non-significant. Finally, female participants were more likely to self-medicate for anxiety. These results suggest widespread self-medication among young adults with likely CUD and underscore the complexity of their cannabis use. The findings have implications for understanding why young adults use cannabis in relation to psychological and physical distress and for accurately treating young adults with cannabis use disorder.
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