Transgenerational epigenetic inheritance in plants.

Transgenerational epigenetic inheritance in plants.
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DOI:
10.1016/j.bbagrm.2011.03.007
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发表时间:
2011-08
影响因子:
4.7
通讯作者:
Luschnig, Christian
Luschnig, Christian
中科院分区:
生物学2区
文献类型:
--
作者:
Hauser, Marie-Theres;Aufsatz, Werner;Jonak, Claudia;Luschnig, Christian

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随着表观遗传机制在发育过程中调控基因表达,以及对生物和非生物胁迫等内外部信号的响应,人们对跨代表观遗传的兴趣日益浓厚。从文献记载较少的轶事及其后果的历史背景开始,我们概述了近60年来收集的关于植物自然发生和诱导的外胚轴和参数化的信息。我们介绍了表观遗传调控的主要参与者及其在控制应激反应中的重要性。从机制的角度总结了不同应激源对表观遗传状态及其跨代遗传的影响。介绍了跨代表观遗传的后果,重点是关于其稳定性的知识,以及与遗传固定突变、重组和基因组重排有关的知识。最后,我们展望了跨代遗传对适应不断变化的环境和实际应用的重要性。这篇文章是题为“植物细胞和发育过程的表观遗传控制”的特刊的一部分。
Interest in transgenerational epigenetic inheritance has intensified with the boosting of knowledge on epigenetic mechanisms regulating gene expression during development and in response to internal and external signals such as biotic and abiotic stresses. Starting with an historical background of scantily documented anecdotes and their consequences, we recapitulate the information gathered during the last 60 years on naturally occurring and induced epialleles and paramutations in plants. We present the major players of epigenetic regulation and their importance in controlling stress responses. The effect of diverse stressors on the epigenetic status and its transgenerational inheritance is summarized from a mechanistic viewpoint. The consequences of transgenerational epigenetic inheritance are presented, focusing on the knowledge about its stability, and in relation to genetically fixed mutations, recombination, and genomic rearrangement. We conclude with an outlook on the importance of transgenerational inheritance for adaptation to changing environments and for practical applications. This article is part of a Special Issue entitled “Epigenetic control of cellular and developmental processes in plants”.
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