Exploration of the host haemostatic system by group A streptococcus: implications in searching for novel antimicrobial therapies.

Exploration of the host haemostatic system by group A streptococcus: implications in searching for novel antimicrobial therapies.
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DOI:
10.1111/j.1538-7836.2011.04316.x
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发表时间:
2011-07
期刊:
Journal of thrombosis and haemostasis : JTH
影响因子:
--
通讯作者:
Sun H
Sun H
中科院分区:
其他
文献类型:
--
作者:
Sun H

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止血系统与宿主对感染的反应密切相关。据报道,许多宿主止血因子,特别是纤溶酶原和纤维蛋白原与各种细菌蛋白结合并相互作用。本文综述了宿主止血因子如纤溶酶原、因子V和纤维蛋白原在宿主防御A组链球菌感染中的作用,并讨论了靶向宿主止血系统对感染性疾病进行治疗干预的潜力。
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