Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders.
Application of DSM-5 criteria for autism spectrum disorder to three samples of children with DSM-IV diagnoses of pervasive developmental disorders.
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DOI：
10.1176/appi.ajp.2012.12020276
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发表时间：
2012-10
期刊：
影响因子：
--
通讯作者：
Lord C
中科院分区：
文献类型：
--
作者：
Huerta M;Bishop SL;Duncan A;Hus V;Lord C
最近，已经提出了对DSM-IV自闭症谱系障碍（ASD）标准的实质性修订，以提高诊断的敏感性和特异性。本研究旨在评估拟议的DSM 5标准使用的样本与PDD和非PDD诊断的儿童。研究参与者来自三个大型数据集，导致4，453名受试者患有DSM-IV广泛性发育障碍的临床诊断，690名受试者患有非PDD诊断（例如，语言障碍，ADHD）。来自ASD症状的父母报告测量（自闭症诊断访谈-修订版）和来自临床观察工具（自闭症诊断观察时间表）的项目与DSM-5标准相匹配，然后用于评估与临床诊断相比的拟议标准的敏感性和特异性。仅基于父母报告数据，拟议的DSM-5标准确定了91%的儿童患有DSM-IV PDD诊断。DSM-5标准的敏感性在ASD儿童的特定亚组中仍然很高，包括女性和4岁以下的儿童。总体而言，DSM-5 ASD标准的特异性为0.53，而DSM-IV的特异性范围为0.24（PDD-NOS标准）至0.53（自闭症障碍标准）。当需要从父母报告和临床观察中获得异常证据时，DSM-5 ASD标准的特异性增加到0.63。基于对现有症状数据的分析，结果表明，大多数目前基于DSM-IV的PDD诊断的儿童仍有资格根据拟议的DSM-5标准进行ASD诊断。与DSM-IV标准相比，DSM-5 ASD标准的特异性有所提高，特别是当父母报告和临床观察均显示异常时。
Recently, substantial revisions to DSM-IV criteria for autism spectrum disorders (ASD) have been proposed in efforts to increase diagnostic sensitivity and specificity. This study sought to evaluate the proposed DSM5 criteria using a sample of children with PDD and non-PDD diagnoses. Study participants were obtained from three large datasets, resulting in 4,453 subjects with DSM-IV clinical diagnoses of Pervasive Developmental Disorder and 690 subjects with non-PDD diagnoses (e.g., language disorder, ADHD). Items from a parent-report measure of ASD symptoms (Autism Diagnostic Interview-Revised) and from a clinical observation instrument (Autism Diagnostic Observation Schedule) were matched to DSM-5 criteria and then used to evaluate the sensitivity and specificity of the proposed criteria when compared to clinical diagnoses. Based on parent-report data only, the proposed DSM-5 criteria identified 91% of children with DSM-IV PDD diagnoses. Sensitivity of DSM-5 criteria remained high in specific subgroups of children with ASD, including females and children under 4. Overall, specificity of DSM-5 ASD criteria was .53, while specificity of DSM-IV ranged from .24 (PDD-NOS criteria) to .53 (Autistic Disorder criteria). When evidence of abnormality was required from both parent-report and clinical observation, specificity of DSM-5 ASD criteria increased to .63. Based on analyses of existing symptom data, results suggest that the majority of children with current DSM-IV-based PDD diagnoses will remain eligible for an ASD diagnosis under the proposed DSM-5 criteria. Compared to DSM-IV criteria for Asperger syndrome and PDD-NOS, specificity of DSM-5 ASD criteria is improved, particularly when abnormalities are evident from both parent report and clinical observation.
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影响因子：
3.9
作者：
Gotham, Katherine;Pickles, Andrew;Lord, Catherine
通讯作者：
Lord, Catherine
自闭症诊断观察表： 提高诊断有效性的修订算法
影响因子：
3.9
作者：
Gotham, Katherine;Risi, Susan;Lord, Catherine
通讯作者：
Lord, Catherine
影响因子：
5.2
作者：
Snow, Anne V.;Lecavalier, Luc
通讯作者：
Lecavalier, Luc
DOI：
10.1016/j.jaac.2011.04.001
发表时间：
2011-06-01
影响因子：
13.3
作者：
Mattila, Marja-Leena;Kielinen, Marko;Moilanen, Irma
通讯作者：
Moilanen, Irma
DOI：
10.1016/j.jaac.2012.01.007
发表时间：
2012-04
影响因子：
13.3
作者：
McPartland JC;Reichow B;Volkmar FR
通讯作者：
Volkmar FR