Aging and HIV/AIDS: neurocognitive implications for older HIV-positive Latina/o adults.
Aging and HIV/AIDS: neurocognitive implications for older HIV-positive Latina/o adults.
复制标题
DOI：
10.1080/08964289.2014.914464
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Morgello S
中科院分区：
文献类型：
--
作者：
Mindt MR;Miranda C;Arentoft A;Byrd D;Monzones J;Fuentes A;Arias F;Rentería MA;Rosario A;Morgello S
近年来，艾滋病毒/艾滋病感染者的年龄越来越大，族裔也越来越多样化。同时，艾滋病毒相关的神经认知（NC）障碍的患病率仍然很高。本研究探讨了年龄和种族对HIV阳性成人NC功能的影响。样本（N = 126; 84例拉丁裔和42例非西班牙裔白色人）完成了一项全面的NC组合测试。生成总体NC和领域平均人口统计学校正t评分。年轻（<50岁）拉丁裔白人和非西班牙裔白人在总体NC功能或NC域上没有显著差异（所有p>.10），效应量通常较小。老年拉丁裔/OS（≥50岁）在处理速度和学习方面的受损程度显著高于老年非西班牙裔白人，总体NC功能和记忆有趋势。此外，效应大小在中等至大范围内（Cohen's d = 0.49 -1.15）。这项研究表明，老年拉丁裔/os是在潜在的更大的风险为NC损害，特别是在处理速度和学习，当与年龄相仿的非西班牙裔白人。
In recent years, HIV/AIDS populations have become older and increasingly more ethnically diverse. Concurrently, the prevalence of HIV-related neurocognitive (NC) impairment remains high. This study examined the effects of age and ethnicity on NC function in HIV-positive adults. The sample (N = 126; 84 Latina/o and 42 Non-Hispanic White) completed a comprehensive NC battery. Global NC and domain average demographically-corrected t-scores were generated. There were no significant differences between Younger (<50 years) Latina/os and non-Hispanic Whites on Global NC function or NC domains (all p's >.10), with generally small effect sizes. Older Latina/os (≥50 years) were significantly more impaired than Older Non-Hispanic Whites on processing speed and learning, with trends in Global NC function and memory. Further, effect sizes fell within the medium to large range (Cohen's d's = .49–1.15). This study suggests that older Latina/os are at potentially greater risk for NC impairment, particularly in processing speed and learning, when compared to similarly-aged non-Hispanic whites.
登录
查看更多内容
影响因子：
3.6
作者：
Benedict, RHB;Schretlen, D;Shpritz, B
通讯作者：
Shpritz, B
影响因子：
3.9
作者：
Benedict, RHB;Schretlen, D;Brandt, J
通讯作者：
Brandt, J
影响因子：
5.9
作者：
Cargill, VA;Stone, VE
通讯作者：
Stone, VE
DOI：
10.1017/s1355617702813157
发表时间：
2002-03-01
影响因子：
2.6
作者：
Manly, JJ;Jacobs, DM;Stern, Y
通讯作者：
Stern, Y
影响因子：
3.8
作者：
Cherner, M;Ellis, R;Heaton, RK
通讯作者：
Heaton, RK